Results 201 to 210 of about 8,893 (235)

GLP-1RA vs DPP-4i Use and Rates of Hyperkalemia and RAS Blockade Discontinuation in Type 2 Diabetes.

open access: yesJAMA Intern Med
Huang T   +7 more
europepmc   +1 more source

GLP-1RA and SGLT2i: Cardiovascular Impact on Diabetic Patients

Current Hypertension Reviews, 2021
Background:Diabetes is a chronic disease with high complexity that demands strategic medical care with a multifactorial risk-reduction approach. Over the past decade, the treatment of type 2 diabetes mellitus (T2DM) has entirely changed. One of the paradigm changes has been the arrival of new drugs that reduce cardiovascular risk beyond the reduction ...
Aschner Pablo   +3 more
openaire   +2 more sources

The GLP-1RAs: From Evolution to Revolution

The Singapore Family Physician, 2022
Research on incretin hormones has advanced considerably over the past few decades. Although the initial molecule – glucose-dependent insulinotropic polypeptide – failed to stimulate insulin secretion in patients with type 2 diabetes, it led to the discovery of glucagon-like peptide 1 (GLP-1). As GLP-1 impacts on various tissues and cells throughout the
openaire   +1 more source

GLP-1RA based therapies in the young and old

Current Opinion in Endocrinology, Diabetes & Obesity
Purpose of review Obesity is recognized as a “gateway” chronic, progressive disease of dysfunctional adipocytes. Glucagon-like peptide-1 receptor agonist-based therapies (GLP1BTs), including glucagon-like peptide-1 receptor agonists (GLP-1 RAs) with/without glucose-dependent insulinotropic polypeptide (GIP), have demonstrated ...
Georgia, Rigas   +2 more
openaire   +2 more sources

Molecular Mechanisms Underlying the Cardiovascular Benefits of SGLT2i and GLP-1RA

Current Diabetes Reports, 2018
In addition to their effects on glycemic control, two specific classes of relatively new anti-diabetic drugs, namely the sodium glucose co-transporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA) have demonstrated reduced rates of major adverse cardiovascular events (MACE) in subjects with type 2 diabetes (T2D) at high ...
Dorrin Zarrin, Khat, Mansoor, Husain
openaire   +2 more sources

Home - About - Disclaimer - Privacy