AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source
Glucagon-like Peptide-1 Receptor Agonists in Liver Transplant Recipients: A Retrospective Cohort Study. [PDF]
Sheashaa H +16 more
europepmc +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
Pneumatosis intestinalis in a patient treated with a glucagon-like peptide-1 receptor agonist and prednisone. [PDF]
Sutton S +3 more
europepmc +1 more source
How Changing Food Preferences and Technology Are Transforming Food Markets
ABSTRACT The foods that consumers purchase and how they purchase food are changing over time. In this article, we discuss how health prioritization and environmental concerns, combined with new technologies, are changing consumers' food preferences and retail choices.
Jill J. McCluskey, Jillian Hyink
wiley +1 more source
Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley +1 more source
Potential Antiarrhythmic Mechanisms of Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs). [PDF]
Li J +11 more
europepmc +1 more source
Can Reprogramming Taste Modulate Excess Food Intake?
Obesity, EarlyView.
Kerstin Rohde‐Zimmermann +1 more
wiley +1 more source
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng +19 more
wiley +1 more source
Glucagon-like peptide-1 medicines in neurological and psychiatric disorders. [PDF]
Fang S, Cui F, Drucker DJ.
europepmc +1 more source

