Results 51 to 60 of about 32,679 (297)

Biochemical Aspects of Non-Starch Polysaccharides

Scientific Papers Animal Science and Biotechnologies, 2023
Polysaccharides are macromolecules of monosaccharides linked by glycosidic bonds. Non-starch polysaccharides (NSP) are principally non-α-glucan polysaccharides of the plant cell wall. They are a heterogeneous group of polysaccharides with varying degrees
Rodica Căpriță, Adrian Căpriță, Călin Julean   +2 more
doaj  

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization

Molecules, 2019
Oyster mushrooms are an interesting source of biologically active glucans and other polysaccharides. This work is devoted to the isolation and structural characterization of polysaccharides from basidiocarps of the cultivated oyster mushroom, Pleurotus ...
Ekaterina Baeva, Roman Bleha, Ekaterina Lavrova, Leonid Sushytskyi, Jana Čopíková, Ivan Jablonsky, Pavel Klouček, Andriy Synytsya   +7 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Chemical Content and Cytotoxic Activity on Various Cancer Cell Lines of Chaga (Inonotus obliquus) Growing on Betula pendula and Betula pubescens

Pharmaceuticals
Chaga mushroom (Inonotus obliquus) is a pathogenic fungus that grows mostly on birch species (Betula pendula Roth and B. pubescens Ehrh.) and has traditionally been used as an anticancer medicine.
Ain Raal, Hedi Kaldmäe, Karin Kütt, Katrin Jürimaa, Maidu Silm, Uko Bleive, Alar Aluvee, Kalev Adamson, Marili Vester, Mart Erik, Oleh Koshovyi, Khan Viet Nguyen, Hoai Thi Nguyen, Rein Drenkhan   +13 more
doaj   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

FT-IR Method Limitations for β-Glucan Analysis

Molecules, 2022
β-glucans are known as biological response modifiers. However, different sources can result in structural differences and as a result differences in their biological activity.
Ruslan Bikmurzin, Rimantė Bandzevičiūtė, Arūnas Maršalka, Andrius Maneikis, Lilija Kalėdienė   +4 more
doaj   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Recognition of fungal glucans by pattern recognition receptors

, 2003
Glucans are (1→3)-β-D linked polymers of glucose that are major constituents of fungal cells walls. Glucans are known to stimulate innate immunity and they are thought to be fungal pathogen associated molecular patterns.
Brown, G. D., Willment, J. A., Herre, J., Williams, D. L., Taylor, Philip Russel, Rice, R., Gordon, P. R.   +6 more
core   +6 more sources

The effect of probiotic bacteria on community composition, microscale pH and matrix architecture in a saliva-derived model of oral biofilm

Journal of Oral Microbiology
Background Streptococcus salivarius K12 and M18 have recently gained interest as probiotic organisms for caries control. This study investigated the impact of S.
Elisabeth Reichardt, Sahar Assar, Mathilde Frost Kristensen, Marie Braad Lund, Sebastian Schlafer   +4 more
doaj   +1 more source