Results 191 to 200 of about 195,219 (266)

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Glucocorticoid-binding Proteins of Rat Liver Cytosol

, 1972
Marjorie A. Koblinsky, Miguel Beato, Mohammed Kalimi, Philip Feigelson   +3 more
openalex   +1 more source

A head start: The relationship of placental factors to craniofacial and brain development

Developmental Dynamics, EarlyView.
Abstract In recent years, the importance of placental function for fetal neurodevelopment has become increasingly studied. This field, known as neuroplacentology, has greatly expanded possible etiologies of neurodevelopmental disorders by exploring the influence of placental function on brain development.
Annemarie Jenna Carver, Martine Dunnwald, Hanna Elizabeth Stevens   +2 more
wiley   +1 more source

Activation of thymocyte glucocorticoid receptors to the steroid binding form. The roles of reduction agents, ATP, and heat-stable factors.

, 1979
Julianne J. Sando, N.D. Hammond, Carol A. Stratford, William B. Pratt   +3 more
openalex   +1 more source

Correlation and Risk Assessment of Inflammation-Based Parameters on Cardiovascular Parameters and Clinical Events in Giant Cell Arteritis: A Retrospective Study. [PDF]

Int J Mol Sci
Schweiger L, Meinitzer A, Szolar D, Brodmann M, Dejaco C, Hafner F, Jud P.   +6 more
europepmc   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

Eye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan, Luo Zhang, Yingshi Piao, Yuan Zhang   +3 more
wiley   +1 more source

SOCS3 and IL-6 mRNA levels in PBMC enhance the early prediction for patients with acute-on-chronic hepatitis B liver failure receiving glucocorticoid therapy. [PDF]

Front Cell Infect Microbiol
Li JH, Wang J, Zhu HX, Zhang F, Tang YN, Wang JW, Fan YC, Liu HH, Wang K.   +8 more
europepmc   +1 more source

Targeting thymic stromal lymphopoietin in nasal type 2 inflammation

Eye &ENT Research, EarlyView.
Abstract Epithelial cell‐derived thymic stromal lymphopoietin (TSLP) plays a crucial role in mediating type 2 immune responses, which is one of the key underlying pathophysiological mechanisms of allergic rhinitis (AR) and most presentations of chronic rhinosinusitis with nasal polyps (CRSwNP).
Xintong Li, Jingjing Guo, Jing Song, Ming Wang   +3 more
wiley   +1 more source

Binding of glucocorticoid receptors to DNA.

, 1975
Guy Rousseau, Stephen J. Higgins, John D. Baxter, David H. Gelfand, Gordon M. Tomkins   +4 more
openalex   +1 more source

Case report and literature review: novel TXNRD2 compound heterozygous variants in familial glucocorticoid deficiency type 5. [PDF]

Front Pediatr
Wang X, Chen X, Chen T, Xie R, Chen QL, Wu H, Wang F.   +6 more
europepmc   +1 more source