Results 191 to 200 of about 248,217 (267)

The interplay between molecular architecture, pharmacology, and suspected adverse drug reactions associated with nonsteroidal androgen antagonists in the United Kingdom

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to correlate potential links between the suspected adverse drug reaction (ADR) profile of licensed nonsteroidal androgen receptor antagonists (NSARA) with their unique chemical properties and known off‐target polypharmacology. Methods Physicochemical and polypharmacology data were curated from the Electronic Medicines Compendium ...
Simrit Dhillon, Albert A. Antolin, Alan M. Jones   +2 more
wiley   +1 more source

Revisiting lupus low disease activity: validation matters, but vindication is imperative. [PDF]

Rheumatology (Oxford)
Parodis I.
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Context-dependent roles of 11β-HSD1 in bone and skeletal muscle diseases. [PDF]

Am J Transl Res
Huo L, Sui W, Wang S, Zhu W, Yang Y, Zhang X, Zhang Y, Wang X.   +7 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Kidney Outcomes With Rituximab Versus Cyclophosphamide in Crescentic ANCA-Associated Glomerulonephritis: Contextualizing Observational Findings. [PDF]

Kidney Int Rep
Brilland B, Augusto JF.
europepmc   +1 more source

Incidence of serious infections, herpes zoster and hepatitis B virus reactivation among patients with SLE: a cohort study using a health claims database in Japan. [PDF]

Lupus Sci Med
Kuwana M, Yabe-Wada T, Hirai T, Kato Y, Yamaguchi Y.   +4 more
europepmc   +1 more source

Genomic and Non-Genomic cross talk between the Gonadotropin- releasing hormone receptor and glucocorticoid receptor signalling pathways

, 2009
Kotitschke, Andrea
core  

Cortisol-resistant CAR-NK cells overcome steroid-induced immunosuppression in lung cancer. [PDF]

Signal Transduct Target Ther
Chakraborty S, Pramanik J, Alviter-Raymundo G, Ward CJ, Shaji SK, Yamashita-Kanemaru Y, Ali FAZ, Banik D, Zhang Z, Veiga-Villauriz C, Homer NZM, Simpson J, Laforest S, Tong S, Zhao Q, Roy J, Iqbal M, Morris AC, Chapman MA, Roychoudhuri R, Hussein H, Klenerman D, Saeb-Parsy K, Mahata B.   +23 more
europepmc   +1 more source

Hair cortisol as a marker of glucocorticoid replacement adequacy in adrenal insufficiency. [PDF]

Front Endocrinol (Lausanne)
Korkmaz Yilmaz M, Tek S, Karatas Kiliccioglu G, Unver Ozkahraman A, Niyazoglu M, Hatipoglu E.   +5 more
europepmc   +1 more source