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2015
: Gluconeogenesis occurs in the liver and kidneys. Gluconeogenesis supplies the needs for plasma glucose between meals. Gluconeogenesis is stimulated by the diabetogenic hormones (glucagon, growth hormone, epinephrine, and cortisol). Gluconeogenic substrates include glycerol, lactate, propionate, and certain amino acids.
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: Gluconeogenesis occurs in the liver and kidneys. Gluconeogenesis supplies the needs for plasma glucose between meals. Gluconeogenesis is stimulated by the diabetogenic hormones (glucagon, growth hormone, epinephrine, and cortisol). Gluconeogenic substrates include glycerol, lactate, propionate, and certain amino acids.
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Gluconeogenesis by the Human Kidney
Nature, 1966GLUCONEOGENESIS has been demonstrated in slices of renal cortex removed from rats fed on ammonium chloride, whereas rats fed on sodium bicarbonate showed a marked reduction in renal glucose production1. Gluconeogenesis by the rat kidney is closely related to the hydrogen ion concentration of the incubation media and it occurs in the presence of a ...
E. Housley, G. M. Aber, Lorna O. Morris
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Disorders of Gluconeogenesis [PDF]
, 1990 Gluconeogenesis is the formation of glucose from noncarbohydrate precursors such as lactate, pyruvate, glycerol, and certain amino acids. It is a continuous process important for maintaining glucose homeostasis during fasting.
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Hepatic gluconeogenesis of the rabbit
Biochemical and Biophysical Research Communications, 1970Abstract Rabbit hepatic mitochondria (m W ), incubated with pyruvate and HCO 3 − produce and liberate to the media sizeable amounts of malate, citrate, and aspartate (if given NH 4 + ). M W from fasted or diabetic rabbits produce and liberate larger amounts of malate. Even though rabbit liver m W possess phosphoenolpyruvate carboxykinase(PEPCK),
Kathleen A. Ebert +2 more
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Gluconeogenesis and Redox State
1971Summary It has been known for some time that the redox state of the NAD-couple in the liver, as measured by the [lactate]/[pyruvate] ratio, moves in the direction of reduction when the rate of gluconeogenesis increases. It was not evident however whether the redox state is of regulatory importance; in other words, whether the change in the redox ...
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Effect of As2O3 on gluconeogenesis
Archives of Toxicology, 19881) The effect of As2O3 and As2O5 on gluconeogenesis from various substrates in the liver and kidney of rats was investigated. 2) A concentration-dependent inhibition by As2O3 was found. The effect was not dependent on the amount of investigated material (hepatocytes or kidney tubules).
L Szinicz, Wolfgang Forth
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Hypoglycemia, Gluconeogenesis and the Brain
1991The purpose of this chapter is to review the role which gluconeo- genesis plays in the response to insulin-induced hypoglycemia and to assess the influence of the brain in driving that response. The chapter is divided into three parts: the response of gluconeogenesis to hypoglycemia; the role of the brain in driving hormone secretion, and as a result ...
D. W. Biggers +3 more
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1995
Gluconeogenesis is defined as the net formation of glucose from non-carbohydrate precursors such as pyruvate, lactate, glycerol, and certain amino acids. It is crucial for survival because glucose, the primary substrate for a number of tissues, most notably the brain, is only available during feeding, and liver glycogen stores can only provide glucose ...
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Gluconeogenesis is defined as the net formation of glucose from non-carbohydrate precursors such as pyruvate, lactate, glycerol, and certain amino acids. It is crucial for survival because glucose, the primary substrate for a number of tissues, most notably the brain, is only available during feeding, and liver glycogen stores can only provide glucose ...
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Gluconeogenesis and nitrogen metabolism in maize
Plant Physiology and Biochemistry, 2018Two pathways can be used by gluconeogenesis in plants: one employs phosphoenolpyruvate carboxykinase (PEPCK) and the other pyruvate orthophosphate dikinase (PPDK). The occurrence-location of these enzymes was determined in developing kernels of maize. PPDK was much more abundant than PEPCK in extracts of whole kernels.
Walker, Robert P. +6 more
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Gluconeogenesis in the suckling rat.
American Journal of Physiology-Endocrinology and Metabolism, 1977Gluconeogenesis from lactate was increased more than twofold in perfused livers and isolated hepatocytes from 10- and 15-day-old suckling rats compared with adult rats and was not increased by fasting. Glucagon (10(-19)-10(-7) M) induced minimal activation of gluconeogenesis in hepatocytes from such animals even though it promoted accumulation of cAMP.
M A Beaudry, J H Exton, J L Chiasson
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