Results 161 to 170 of about 25,604 (214)
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Glucosamine and Chondroitin Sulfate
Rheumatic Disease Clinics of North America, 2011Glucosamine and chondroitin sulfate, components of normal cartilage that are marketed as dietary supplements in the United States, have been evaluated for their potential role in the treatment of osteoarthritis. Due to claims of efficacy, increased prevalence of osteoarthritis, and a lack of other effective therapies, there has been substantial ...
Daniel O Clegg
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Risk assessment for glucosamine and chondroitin sulfate
Regulatory Toxicology and Pharmacology, 2007Glucosamine and chondroitin sulfate are two popular dietary ingredients present in dietary supplements intended to support joint health. A large body of human and animal research suggests that oral intakes of these ingredients, either alone or in combination, reduces joint pain and improves mobility in persons with osteoarthritis.
John N Hathcock, Andrew Shao
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The preparation and antioxidant activity of glucosamine sulfate
Chinese Journal of Oceanology and Limnology, 2009Glucosamine sulfate was prepared from glucosamine hydrochloride that was produced by acidic hydrolysis of chitin by ion-exchange method. Optical rotation and elemental analysis characterized the degree of its purity. In addition, the antioxidant potency of chitosan derivative-glucosamine sulfate was investigated in various established in vitro systems,
Ronge Xing, Shengbao Cai, Huahua Yu
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Objective: Pharmacokinetic data on glucosamine are scant, limiting the understanding of glucosamine sulfate mechanism of action in support of its treatment effects in osteoarthritis.
Stefano Persiani +2 more
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SummaryObjectiveTo evaluate the efficacy and safety of chondroitin sulfate and/or glucosamine hydrochloride in alleviating symptoms and improving the dysfunction of Kashin-Beck disease (KBD) patients.MethodsWe undertook a cluster-randomized, placebo ...
Ming Yang, Birong Dong
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Systematic Analysis of Pharmaceutical Preparations of Chondroitin Sulfate Combined with Glucosamine
Glycosaminoglycans are carbohydrate-based compounds widely employed as nutraceuticals or prescribed drugs. Oral formulations of chondroitin sulfate combined with glucosamine sulfate have been increasingly used to treat the symptoms of osteoarthritis and ...
Gustavo R C Santos +2 more
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Sulfate could mediate the therapeutic effect of glucosamine sulfate
Metabolism, 2001Glucosamine sulfate is a controversial osteoarthritis remedy that is presumed to stimulate articular cartilage glycosaminoglycan synthesis by increasing glucosamine concentrations in the joint space. However, this is not plausible because even large oral doses of the product have no effect on serum glucosamine concentrations.
L J, Hoffer +4 more
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Glucosamine Sulfate and Chondroitin Sulfate for the Treatment of Osteoarthritis
The Journal of the Korean Rheumatism Association, 2008Osteoarthritis (OA) is the most common form of arthritis often associated with morbidity, disability, functional impairment and impaired quality of life. A new perspective in OA management is to delay disease progression by modifying joint structure. Glucosamine sulfate (GS) and chondroitin sulfate (CS) have attracted a lot of interest as a specific ...
Young Ho Lee, Jong Dae Ji, Gwan Gyu Song
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Effect of Glucosamine Sulfate on Hip Osteoarthritis
Annals of Internal Medicine, 2008The effectiveness of glucosamine sulfate as a symptom and disease modifier for osteoarthritis is still under debate.To assess whether glucosamine sulfate has an effect on the symptoms and structural progression of hip osteoarthritis during 2 years of treatment.Randomized, controlled trial.Primary care in the Netherlands.222 patients with hip ...
Rozendaal, Rianne +9 more
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Glucosamine sulfate—environmental antibacterial activity
Clinical Rheumatology, 2009We have recently showed antibacterial activity against E. coli in vitro of a trademark Mega-Gluflex-containing glucosamine sulfate (GS) and chondroitin sulfate (CS). The purpose of this study was to examine the antibacterial activity of GS as a new trademark Arthryl (Manufacturer Rottapharm Ltd, Ireland; Distributor in Israel Rafa Laboratories Ltd) in ...
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