Results 111 to 120 of about 298,051 (300)
Psychiatry and Clinical Psychopharmacology, 2021 Objective: Effects of chlorpromazine and haloperidol on erythrocyte glucose 6-phosphate dehydrogenase enzyme activity were investigated in invitro conditions. Methods: Glucose 6- phosphate dehydrogenase was purified from human erythrocyte.
Mehmet Emin Büyükokuroğlu +4 more
doaj
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Advanced Science, EarlyView.Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites. [PDF]
, 2019 Age and Alzheimer's disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation.
Brewer, Gregory J, Dong, Yue
core
Advanced Science, EarlyView.In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu +11 more
wiley +1 more source
Enhanced Eryptosis in Glucose-6-Phosphate Dehydrogenase Deficiency
Cellular Physiology and Biochemistry, 2021 Ghada Bouguerra +6 more
doaj +1 more source
Journal of Medical Case ReportsBackground Naphthalene is an aromatic hydrocarbon that potentially produces methemoglobinaemia but rarely causes hemolysis, especially in children with underlying glucose-6-phosphate dehydrogenase deficiency.
Kavinda Dayasiri +2 more
doaj +1 more source
The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus
Advanced Science, EarlyView.BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang +8 more
wiley +1 more source
Ischemic Priapism Associated with Glucose-6-phosphate Dehydrogenase Deficiency: A Case Report
Oman Medical JournalIschemic priapism is a male urologic emergency. Most cases have been linked to genetic conditions such as sickle cell disease and (much more rarely) glucose-6-phosphate dehydrogenase deficiency, and the use of certain drugs. Here, we report the case of a
Noor Nabi Junejo +3 more
doaj +1 more source
Advanced Science, EarlyView.A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan +24 more
wiley +1 more source
Effect of diet composition and ration size on key enzyme activities of glycolysis-gluconeogenesis, pentose phosphate pathway and amino acid metabolism in liver of Sparus aurata [PDF]
, 2013 The effects of diet composition and ration size on the activities of key enzymes involved in intermediary metabolism were studied in the liver of gilthead sea bream (Sparus aurata). Highcarbohydrate, low-protein diets stimulated 6-phosphofructo 1-kinase (
Cantó, Elisabet +5 more
core