Results 121 to 130 of about 352,162 (366)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Glucose-6-Phosphate Dehydrogenase Deficiency in Icteric Newborns at the Essos-Yaoundé-Cameroon Hospital

, 2023
Josué Simo Louokdom, Romaric De Manfouo Tuono, Prisca Yngrid Tekam Meupia, Maï-Pamela Tumchou Mekieje, Maryline Seuko Njopwouo, Pascal Dieudonné Chuisseu Djamen   +5 more
openalex   +2 more sources

Intravenous infusions of glucose stimulate key lipogenic enzymes in adipose tissue of dairy cows in a dose-dependent manner [PDF]

, 2013
The present study was investigated whether increasing amounts of glucose supply have a stimulatory effect on the mRNA abundance and activity of key lipogenic enzymes in adipose tissue of midlactation dairy cows.
Al-Trad, Bahaa, Aschenbach, Jörg R., Carra, Mirja, Fürll, Manfred, Gäbel, Gotthold, Penner, Gregory B., Wittek, Thomas   +6 more
core   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

INCIDENCE OF ERYTHROCYTE GLUCOSE-6-PHOSPHATE- DEHYDROGENASE DEFICIENCY

Iranian Journal of Public Health, 1974
In a survey carried out to establish the incidence of erythrocyte glucose­ 6-phosphate-dehydrogenase deficiency, 738 professional blood donors of Tehran were examined.
Sh. Rahbar, M. Mir Ahmadian, P. Bahadory, F. Berelian   +3 more
doaj  

Study of Glucose-6-phosphate Dehydrogenase (G6PD) Status in Preeclampsia

Bangabandhu Sheikh Mujib Medical University Journal, 2010
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the common enzymopathy and may be one of the risk factor for complicated pregnancy.
Kazi Salma Binte Faruky, Noorzahan Begum, Shelina Begum, Taskina Ali, Sultana Ferdousi, Ahsanul Haq Amin   +5 more
doaj   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Glucose-6-Phosphat-Dehydrogenase-Mangel

Swiss Medical Forum ‒ Schweizerisches Medizin-Forum, 2016
Immer haufiger kommen Patienten in die Praxis und ins Spital, die einen G6PD-Mangel aufweisen und bei denen es wichtig ist zu wissen, welche Medikamente poten­tiell gefahrlich sind. In diesem Ubersichtsartikel werden der G6PD-Mangel, die ­Diagnostik und die Medikamente, die zu vermeiden sind, beschrieben.
Sarah Hofmann, Andreas Buser, Anne Taegtmeyer   +2 more
openaire   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Homozygous ?- thalassemia with Glucose 6 phosphate dehydrogenase deficiency: A case report.

Mediterranean Journal of Hematology and Infectious Diseases, 2014
The thalassemias and glucose 6 phosphate dehydrogenase deficiency are among the most common disorders worldwide. The marked oxidative stress caused by ?-thalassemia, that is apparently incompatible with glucose 6 phosphate dehydrogenase deficiency was ...
Jitender Mohan Khunger, Rohit Kapoor, Rekha Singh, Monica Khunger, Renu Saxena   +4 more
doaj