Results 101 to 110 of about 103,735 (293)

Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt

open access: yesAnnals of Saudi Medicine, 2017
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations.
Soheir Abo Elella   +3 more
doaj   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma   +15 more
wiley   +1 more source

Methemoglobinemia and Glucose-6-phosphate Dehydrogenase Deficiency in a Neonate

open access: yesIndian Pediatrics Case Reports
Background: Methemoglobinemia is a condition where heme iron is oxidized from ferrous to ferric state, leading to hypoxia. Commonly due to drugs and toxins, it may rarely occur due to glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Saurabh Aggarwal   +3 more
doaj   +1 more source

Genetic disorders and malaria in Indo-China region [PDF]

open access: yes, 2008
High prevalence of malaria in Southeast Asia including Thailand is believed to be a major public health problem to the population in this area since time immemorial.
Viroj Wiwanitkit
core  

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

open access: yesAdvanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang   +4 more
wiley   +1 more source

Enhanced Eryptosis in Glucose-6-Phosphate Dehydrogenase Deficiency

open access: yesCellular Physiology and Biochemistry, 2021
Ghada Bouguerra   +6 more
doaj   +1 more source

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

open access: yesNature Communications, 2018
Glucose-6-phosphate dehydrogenase (G6PD) deficiency provides insufficient protection from oxidative stress, contributing to diverse human pathologies. Here, the authors identify a small molecule that increases the activity and/or stability of mutant G6PD
Sunhee Hwang   +9 more
doaj   +1 more source

Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

open access: yes, 2009
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew   +5 more
core   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

open access: yesAdvanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun   +5 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase deficiency among children attending the Emergency Paediatric Unit of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

open access: yesInternational Journal of General Medicine, 2013
IZ Isaac,1 AS Mainasara,2 Erhabor Osaro,1 ST Omojuyigbe,1 MK Dallatu,3 LS Bilbis,3 TC Adias4 1Department of Haematology and Transfusion Medicine, 2Department of Chemical Pathology, 3Department of Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria;
Isaac IZ   +6 more
doaj  

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