Results 111 to 120 of about 50,967 (156)
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Glucose-6-phosphate dehydrogenase deficiency
The Lancet, 2008Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect, being present in more than 400 million people worldwide. The global distribution of this disorder is remarkably similar to that of malaria, lending support to the so-called malaria protection hypothesis.
M.D. Cappellini, G. Fiorelli
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Glucose-6-phosphate dehydrogenase deficiency
Critical Reviews in Oncology/Hematology, 1995Glucose-6-phosphate dehydrogenase (G6PD) is an X chromosome-linked enzyme and the key enzyme of the pentose phosphate pathway. The G6PD functions to reduce nicotinamide-adenine-dinucleotide phosphate (NADP) to a reduced form (NADPH), while it oxidizes glucosed-phosphate (G6P) in the hexose monophosphate shunt.
J G, Chang, T C, Liu
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Favism and Glucose-6-Phosphate Dehydrogenase Deficiency
New England Journal of Medicine, 2018Favism and Glucose-6-Phosphate Dehydrogenase Deficiency When persons with G6PD deficiency eat fava beans, acute hemolytic anemia may develop. It is caused by the generation of free radicals from the metabolism of glucosides in the beans. The free radicals damage red cells, resulting in intravascular and extravascular lysis.
Michael, Steiner +2 more
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Glucose-6-phosphate dehydrogenase deficiency in Iraq
Human Genetics, 1981Glucose-6-phosphate dehydrogenase was tested in the blood of 305 males and 394 females, with Beutler's fluorescent spot test being used for screening. The percentage of deficiency was estimated at 12.4% for males and 8.8% for females of all ages; it was, however, highest among children and lowest among those over 50 years.
H A, Hamamy, T K, Saeed
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Muscle glucose-6-phosphate dehydrogenase deficiency
Journal of Neurology, 1989Muscle glucose-6-phosphate dehydrogenase (G6PD) deficiency is described in four clinically heterogeneous patients: an athlete who developed myoglobinuria after physical exercise; a 7-year-old, mildly mentally retarded boy, who had episodes of dark urine and high creatine kinase; and two brothers of Sardinian origin, the elder showing moderate exercise ...
N, Bresolin +9 more
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Glucose-6-phosphate dehydrogenase deficiency in Malayans
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1964Abstract The frequency of G-6-PD deficiency in 2,030 males of different racial groups in Malaya was studied. The frequencies in normal healthy males were 2.4 per cent. in Chinese, 2.0 per cent. in Malays and 1 per cent. in Indians. In male hospital patients the frequencies were 4.2 per cent. in Chinese, 3.4 per cent. in Malays and 0.4 per cent.
L L, ENG, T S, TI
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Glucose–6–phosphate dehydrogenase deficiency in India
The Indian Journal of Pediatrics, 2004Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the commonest red cell enzymopathy in humans and has an X-linked inheritance. It has been reported from India more than 30 years ago and the prevalence varies from 0-27% in different caste, ethnic and linguistic groups.
Dipika, Mohanty +2 more
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Glucose‐6‐Phosphate Dehydrogenase Deficiency and Myelofibrosis
Scandinavian Journal of Haematology, 1973A presentation is made of a patient with myelofibrosis and chronic haemolytic anaemia. Known causes of haemolysis in combination with myelofibrosis were excluded. A hereditary red cell glucose‐6‐phosphate dehydrogenase (G‐6‐PD) deficiency was found. The case history is reported, along with the results of haematological investigations in the affected ...
O, Selroos, P, Vuopio
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Glucose-6-phosphate dehydrogenase deficiency and malaria
Journal of Molecular Medicine, 1998Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme that is essential for a cell's capacity to withstand oxidant stress. G6PD deficiency is the commonest enzymopathy of humans, affecting over 400 million persons worldwide. The geographical correlation of its distribution with the historical endemicity of malaria suggests that 66PD ...
C, Ruwende, A, Hill
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Glucose-6-Phosphate Dehydrogenase Deficiency in a Dog
Enzyme, 2017After screening 3,300 dogs, one animal with a mild deficiency of erythrocyte G6PD was detected. Although it had several clinical problems for 2 months, no abnormality could be directly attributable to the reduced enzymatic activity. Biochemically the mutant was electrophoretically slower but within the normal range for K(m)-G6P, K(m)-NADP, use of 2 ...
J E, Smith, K, Ryer, L, Wallace
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