Results 291 to 300 of about 4,211,438 (402)

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

open access: yesScience, 2005
R. Shaw   +7 more
semanticscholar   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

open access: yesAdvanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen   +5 more
wiley   +1 more source

Rotating Liquid Marble Microreactors for Enhanced Enzymatic Reactions

open access: yesAdvanced Functional Materials, EarlyView.
Dynamic magnetic liquid marbles (LMs), stabilized by hydrophobic magnetic proteinaceous colloidosomes, function as effective microreactors for enzymatic processes. Precise magnetic manipulation allows for the rotation of these LMs, enhancing the efficiency of the enzymatic cascade reaction both at the air/water interface and within biphasic enzyme ...
Weijie Jiang   +5 more
wiley   +1 more source

Hyperglycemia selectively increases cerebral non-oxidative glucose consumption without affecting blood flow. [PDF]

open access: yesJ Cereb Blood Flow Metab
Blazey T   +6 more
europepmc   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson   +12 more
wiley   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

open access: yesAdvanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri   +4 more
wiley   +1 more source

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