Genomic and Transcriptomic Insights Into the Autotrophic Metabolism on H<sub>2</sub> + CO<sub>2</sub> or CO of the Thermophilic Acetogenic Model Organism Moorella thermoacetica. [PDF]
Rosenbaum FP +3 more
europepmc +1 more source
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi +15 more
wiley +1 more source
Direct Production of 2-Butanol from Glucose by Recombinant <i>Klebsiella pneumoniae</i> Strains. [PDF]
Gergov E +4 more
europepmc +1 more source
Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions
ABSTRACT To advance understanding of cellular metabolism and reduce batch‐to‐batch variability in cell culture processes, this study introduces a multi‐scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell cultures undergoing metabolic phase transitions.
Keqi Wang, Sarah W. Harcum, Wei Xie
wiley +1 more source
Metabolic reprogramming promotes <i>Staphylococcus aureus</i> serum resistance. [PDF]
Fenn SJ, Douglas EJA, Massey RC.
europepmc +1 more source
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino +6 more
wiley +1 more source
Metatranscriptome profile of agricultural microbial communities enriched for plastitrophy. [PDF]
Olabemiwo FA +7 more
europepmc +1 more source
Thermodynamic Evaluation of Dual Substrate Growth
ABSTRACT Various C₁–C₂ compounds are increasingly available through electrochemical reduction of CO2. Although not always suitable as a sole substrate, these compounds can supplement a primary substrate like glucose to enhance microbial growth. Yet, the mechanisms underlying the effects of dual substrate consumption on growth rate and growth yield ...
Marit A. Verheijen +3 more
wiley +1 more source
Structural insights into cellobiose dehydrogenases of a non-lignocellulolytic fungus and their transcriptional dynamics across different nutritional modes. [PDF]
Kruhler N +7 more
europepmc +1 more source
Nicotinamide Reverses the Warburg Effect in CHO Cell Culture
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey +7 more
wiley +1 more source

