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The genetics of the glucose intolerance disorders
The American Journal of Medicine, 1981Genetic heterogeneity, the concept that diabetes can have many different causes, was first suggested by the existence of rare genetic syndromes with diabetes, ethnic differences in clinical features and genetic heterogeneity of animal models. Genetic heterogeneity is now considered to be firmly established by family, twin, metabolic, immunologic and ...
J I, Rotter, D L, Rimoin
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Glucose intolerance in women with preeclampsia
Acta Obstetricia et Gynecologica Scandinavica, 1998We have previously shown that women with proteinuric hypertension of pregnancy (preeclampsia) have increased circulating levels of triglycerides and free fatty acids. Preeclampsia has, therefore, several features in common with the insulin resistance syndrome.
B, Lorentzen +3 more
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The Thyroid and Glucose Intolerance in Uremia
Annals of Internal Medicine, 1983Excerpt To the editor: We read with interest the recent report by the UCLA conference on thyroid function in nonthyroidal illness (1).
S, De Marchi, E, Cecchin, M, Borean
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Glucose Intolerance in Hypernatremic Rats
Diabetes, 1968A study has been made of the effect of hypernatremia on carbohydrate metabolism in the rat. It was shown that rats rendered hypernatremic by subcutaneous injections of hypertonie sodium solutions manifest increased fasting blood glucose levels, as well as a decreased ability to dispose of an exogenous glucose load. The mechanism by which
M, Nitzan, S, Zelmanovsky, P, Tikva
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Hyperinsulinemia in glucose intolerance: Is it true?
Journal of Endocrinological Investigation, 1994To evaluate whether beta-cell hyperfunction characterizes glucose intolerant states per se independent of fasting glycemia, we conducted a case-control study among 430 subjects who were classified, by NDGG criteria, as having normal glucose tolerance (n = 230, 130M/130F), nondiagnostic tolerance (NDT, n = 100, 50M/50F) and impaired glucose tolerance ...
GIUGLIANO, Dario +5 more
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Glucose Intolerance with Atypical Antipsychotics
Drug Safety, 2002Previous studies have suggested that the atypical antipsychotics clozapine and olanzapine may be associated with an increased risk of glucose intolerance and diabetes mellitus. Early studies have also suggested an association between use of conventional antipsychotics and the development of glucose intolerance.To examine quantitatively the association ...
Karin, Hedenmalm +4 more
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Postpartum glucose intolerance: an updated overview
Endocrine, 2017The prevalence of type 2 diabetes mellitus has increased worldwide over the past three decades, as a consequence of the more westernized lifestyle, which is responsible for the increasing obesity rate in the modern adult's life. Concomitant with this increase there has been a gradual rise in the overall prevalence of gestational diabetes mellitus, a ...
Ida Pastore +3 more
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Glucose intolerance in acute infections
Journal of Internal Medicine, 1989Abstract. To evaluate the influence of an infective agent, severity of infection and the age of the patient on infection‐induced glucose intolerance, concentrations of fasting blood glucose, serum insulin (n = 31) and plasma glucagon (n = 22) were measured and the oral glucose tolerance test (OGTT) was carried out (n = 26) during acute and ...
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Pathogenesis of glucose intolerance in uremia
Metabolism, 1978The pathogenesis of glucose intolerance in uremia was examined with the glucose clamp technique. Hyperglycemic clamp (n = 8): The plasma glucose concentration is acutely raised and maintained at 125 mg/dl above basal levels. Under these steady state conditions the glucose infusion rate, M, equals the amount of glucose metabolized: Predialysis M ...
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