Results 101 to 110 of about 9,284,972 (304)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Kontinuierliche Glukosemessung (CGM – Continuous Glucose Monitoring) bei Diabetes mellitus [PDF]

, 2016
This position statement represents the recommendations of the Austrian Diabetes Association regarding the clinical diagnostic and therapeutic application, safety and benefits of continuous subcutaneous glucose monitoring systems in patients with diabetes
Schütz-Fuhrmann, Ingrid, Prager, Rudolf, Zlamal-Fortunat, Sandra, Hofer, Sabine, Stadler, Marietta, Laimer, Markus, Bischof, Martin, Rami-Merhar, Birgit, Weitgasser, Raimund   +8 more
core   +2 more sources

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Machine Learning‐assisted Interpretation of Scan‐Rate‐dependent Glucose Sensing on Nickel Cobalt Oxide/Porous Carbon Modified Screen‐printed Electrodes

Electrochemical Science Advances
Artificial intelligence (AI) is being increasingly applied in diabetes care, particularly in glucose monitoring and management. However, the reliability of AI‐driven glucose sensing is often limited by sensor inaccuracy due to the plethora of ...
Shahin Faruk, Udhaya Ganesh Pitchai Kaveri, Manoj T., Krishnamoorthi Makkithaya, Harishkumar Madhyastha, Sundaram Gunasekaran, Mysore Sridhar Santosh, Aarti Sripathi Bhatt, Bistuvalli Chandrashekarappa Revanasidappa   +8 more
doaj   +1 more source

Glucose Monitoring During Pregnancy [PDF]

, 2010
Self-monitoring of blood glucose in women with mild gestational diabetes has recently been proven to be useful in reducing the rates of fetal overgrowth and gestational weight gain.
J. Seth Hawkins, Hawkins, J. Seth
core   +1 more source

Outcome of an educational training programme on blood glucose monitoring among nurses in the management of hypoglycaemia and hyperglycemia [PDF]

, 2020
Introduction. Diabetes mellitus is a chronic metabolic disorder that can lead to an increased length of hospital stay, delayed healing, and exacerbation of co-morbidities with complications arising if not properly managed.
Onianwa, P.O., Akintola, G.O., Ojerinde, O.E., Gbenro-Ayodeji, A., Sodipo, T.O., Akanbi, F.O.M., Nkom, A.T., Ojemola, O.E., Are, O.O., Ayorinde, M.O., Patricia Obiajulu Onianwa, Ogonna Eze Ojerinde, Alice Nkom, Mary Oyenike Ayorinde, Mary Ayorinde, Grace Akintola, Oladotun Ojemola, Oladotun Eniola Ojemola, Folashade Omobisi Mary Akanbi, Alice Taiwo Nkom, Patricia Onianwa, Adesola Gbenro-Ayodeji, Folashade Akanbi, Grace Oyeladun Akintola, Temitope Omowunmi Sodipo, Olufunke Are, Olufunke Olabisi Are   +26 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Glucose oxidase immobilized on magnetic nanoparticles: Nanobiosensors for fluorescent glucose monitoring

, 2017
The authors describe enzyme based nanobiosensors for continuous monitoring of glucose, with the long term goal of using them as smart diagnostic tattoos.
Marcos, Susana, Cebolla, Vicente, Galbán, Javier, Susana de Marcos, Melisa del Barrio, Vicente Cebolla, Jesús M. de la Fuente, Valeria Grazú, María Moros, Del Barrio Redondo, Melisa, Moros, María, Puertas, Sara, Grazú, Valeria, Sara Puertas, de la Fuente, Jesús, Javier Galbán   +15 more
core   +1 more source