Results 71 to 80 of about 679,700 (302)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Continuous glucose monitoring

BMJ, 2023
Dana M Lewis, Tamara K Oser, Benjamin J Wheeler   +2 more
openaire   +4 more sources

Teaching Casual Random Blood Glucose Screening to Second-Year Dental Students [PDF]

, 2009
In our project, archived casual random blood glucose levels of second-year dental students who were taught the mechanics of self-testing were retrieved.
Kassab, Moawi M, Lynch, Denis P, Radmer, Thomas W, Walsh, Martin   +3 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Simple Photometer as a Helping Device in Measuring Blood Glucose [PDF]

, 2014
Measurement of non-invasive blood glucose is one way to increase the frequency of self-monitoring of blood glucose (SMBG). For NIR reflectance spectroscopy, its application in non-invasive constrained by high value of standard error of prediction.
Ibrahim, A. S. (Anwar), Prafiantini, E. (Erfi), Priyanto, D. (Dendi), Riyanto, S. A. (Subari), Suprapto, A. P. (Akmal), Tedjo, A. (Aryo)   +5 more
core  

A deep learning approach to diabetic blood glucose prediction

, 2017
We consider the question of 30-minute prediction of blood glucose levels measured by continuous glucose monitoring devices, using clinical data. While most studies of this nature deal with one patient at a time, we take a certain percentage of patients ...
Mhaskar, H. N., Pereverzyev, S. V., van der Walt, M. D.   +2 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Serum Biochemical Phenotypes in the Domestic Dog [PDF]

, 2016
The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences.
Chang, Y M, Garden, O A, Hadox, E, Szladovits, B   +3 more
core   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Definition of the upper reference limit of glycated albumin in blood donors from Italy [PDF]

, 2017
Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and ...
Agnello, Luisa, Bellia, Chiara, Bivona, Giulia, Ciaccio, Marcello, Cosma, Chiara, Plebani, Mario, Sasso, Bruna Lo, Zaninotto, Martina   +7 more
core   +1 more source