Results 111 to 120 of about 166,533 (261)

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

Silicon-Based Glucose Oxidase Working Electrode for Glucose Sensing

open access: yesACS Omega, 2019
Jacqueline Soto   +2 more
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

open access: yesAdvanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang   +12 more
wiley   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

open access: yesAdvanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa   +11 more
wiley   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu   +16 more
wiley   +1 more source

Efeito da glucose-oxidase sobre a produção de celulase

open access: yesSemina: Ciências Sociais e Humanas, 1983
With the object to decrease the glucose inhibitory effect over cellulose, Trichoderma reesei QM 9414 was cultivated in the presence of 72,000 units (4g) of glucose-oxidase per liter culture media.
Rui Sérgio dos Santos Ferreira da Silva   +3 more
doaj  

Comparison of Advantage® Blood Glucose with Plasma Glucose Measured by Glucose Oxidase Method

open access: yesJournal of Associated Medical Sciences, 2015
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Pisit Mamjuntra
doaj  

Simultaneous GCN4 co-expression and promoter optimization enhance glucose oxidase production in <i>Pichia pastoris</i>. [PDF]

open access: yesIran J Microbiol
Ghafari N   +6 more
europepmc   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

open access: yesAngewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber   +4 more
wiley   +1 more source

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