Results 201 to 210 of about 116,203 (264)

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

Advanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg, F. Max Yavitt, Ezgi Bakirci, Khoon Lim, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +5 more
wiley   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

Advanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai, Lorely Garcia‐Sanchez, Maryam Amini, Lara Luana Teruel‐Enrico, Silke Siegrist, Aránzazu del Campo, Sara Trujillo   +6 more
wiley   +1 more source

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Holographic glucose sensors

Biosensors and Bioelectronics, 2005
A novel holographic sensor system capable of detecting dynamic changes in glucose concentration has been developed. The hologram is recorded within a bio-compatible hydrogel matrix containing phenylboronic acid derivatives. On binding glucose, the colour of the hologram red-shifts to longer wavelengths as the hydrogel expands and this colour change is ...
Satyamoorthy, Kabilan, Alexander J, Marshall, Felicity K, Sartain, Mei-Ching, Lee, Abid, Hussain, Xiaoping, Yang, Jeff, Blyth, Njeri, Karangu, Karen, James, Jimmy, Zeng, Dawn, Smith, Angelika, Domschke, Christopher R, Lowe   +12 more
openaire   +2 more sources

Electrocatalytic glucose sensor

Medical & Biological Engineering & Computing, 1994
An electrocatalytic glucose sensor for in vivo application has been developed. The sensor is a flow-through cell with three electrodes and can be integrated into a blood vessel. The principle of measurement is based on the direct electrochemical oxidation of glucose at a membrane-covered noble-metal electrode.
W, Lager, I, von Lucadou, W, Preidel, L, Ruprecht, S, Saeger   +4 more
openaire   +2 more sources

Implantable glucose sensor

Journal of Biomedical Engineering, 1983
Two new approaches for construction and testing of a miniature in vivo implantable glucose sensor are described. The first approach is to immobilize glucose oxidase onto a platinum wire, coated with special glass (Corning), and to cover the immobilized enzyme with a thin layer of polymer to prevent large molecules from poisoning the electrode.
E, Wilkins, M G, Wilkins
openaire   +2 more sources

Glucose‐sensitive holographic sensors

Journal of Molecular Recognition, 2004
AbstractHolographic sensors for monitoring glucose were fabricated from hydrogel films containing chemical ligands based on phenylboronic acid. The films were transformed into reflection holograms using a diffusion method coupled with exposure to laser light.
S, Kabilan, J, Blyth, M C, Lee, A J, Marshall, A, Hussain, X-P, Yang, C R, Lowe   +6 more
openaire   +2 more sources

An acoustic glucose sensor

Biosensors and Bioelectronics, 2012
In vivo glucose monitoring is required for tighter glycaemic control. This report describes a new approach to construct a miniature implantable device based on a magnetic acoustic resonance sensor (MARS). A ≈ 600-800 nm thick glucose-responsive poly(acrylamide-co-3-acrylamidophenylboronic acid) (poly(acrylamide-co-3-APB)) film was polymerised on the ...
Ruifen, Hu, Adrian C, Stevenson, Christopher R, Lowe   +2 more
openaire   +2 more sources

Implantable Electrocatalytic Glucose Sensor

Hormone and Metabolic Research, 1994
An electrocatalytic glucose sensor for in vivo application has been developed to determine the glucose level in blood and further to control the insulin dosage in a closed loop system for diabetes therapy. The principle of the electrocatalytic glucose sensor is based on the direct electrochemical oxidation of glucose at a membrane-covered platinum ...
W, Lager, I, von Lucadou, H, Nischik, T, Nowak, W, Preidel, L, Ruprecht, M J, Stanzel, V, Tegeder   +7 more
openaire   +2 more sources