Results 31 to 40 of about 127,122 (260)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Transdermal Microneedle Array-based Sensor for Real Time Continuous Glucose Monitoring

open access: yesInternational Journal of Electrochemical Science, 2015
We fabricated a low cost, low power consuming and easy to use continuous glucose monitoring system in this study. The transdermal sensor consists of an electrochemical sensing unit, a signal-processing unit and a power supply unit.
Kuo-Yuan Hwa   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Totally organic and self-powered glucose sensor based on energy-harvesting enzymatic biofuel cells

open access: yesMechanical Engineering Journal
Self-powered biosensors that operate independently of external power supplies are gaining significant attention for wearable and point-of-care applications.
Hitomi YAHAGI   +4 more
doaj   +1 more source

Microsensor in Microbioreactors: Full Bioprocess Characterization in a Novel Capillary-Wave Microbioreactor

open access: yesBiosensors, 2022
Microbioreactors (MBRs) with a volume below 1 mL are promising alternatives to established cultivation platforms such as shake flasks, lab-scale bioreactors and microtiter plates.
Kevin Viebrock   +9 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The glucose sensor in HIT cells is the glucose transporter [PDF]

open access: yesFEBS Letters, 1987
The nature of the rate‐limiting step for glucose utilization by the clonal insulin‐producing cell line HIT‐T15 has been investigated. In contrast to the situation in islets of Langerhans, we find that the HIT cell glucose metabolism is limited by the rate of entry of glucose into the cell. This is evidenced by the low rate of sugar transport and by the
Ashcroft, Stephen J.H., Stubbs, Mark
openaire   +2 more sources

2D Au Nanosphere Arrays/PVA-PBA-Modified-Hydrogel Composite Film for Glucose Detection with Strong Diffraction Intensity and Linear Response

open access: yesNanomaterials, 2019
A novel glucose sensor was reported that consisted of two-dimensional (2D) Au nanosphere arrays and glucose-responsive hydrogel film. This sensor exhibited an intense diffraction signal and an obvious diffraction color on a quartz slide due to the strong
Wenjuan Li   +3 more
doaj   +1 more source

The Application of Wearable Glucose Sensors in Point-of-Care Testing

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Diabetes and its complications have become a worldwide concern that influences human health negatively and even leads to death. The real-time and convenient glucose detection in biofluids is urgently needed.
Sheng Zhang   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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