Results 91 to 100 of about 680,023 (357)

Effects of pre-exercise carbohydrate consumption on metabolism during exercise [PDF]

, 2016
It is well documented that consuming carbohydrates (CHO) prior to exercise has been shown to alter metabolism. There are many ways that CHO ingestion affects substrate utilization and blood glucose dynamics at the start of exercise.
Montzingo, Luke James
core   +1 more source

Isosteres of ester derived glucose uptake inhibitors

Bioorganic & Medicinal Chemistry Letters, 2020
Glucose transporters (GLUTs) facilitate glucose uptake and are overexpressed in most cancer cells. Inhibition of glucose transport has been shown to be an effective method to slow the growth of cancer cells both in vitro and in vivo. We have previously reported on the anticancer activity of an ester derived glucose uptake inhibitor.
Dennis A, Roberts, Liyi, Wang, Weihe, Zhang, Yi, Liu, Pratik, Shriwas, Yanrong, Qian, Xiaozhuo, Chen, Stephen C, Bergmeier   +7 more
openaire   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Impact of assimilable nitrogen availability in glucose uptake kinetics in Saccharomyces cerevisiae during alcoholic fermentation

Microbial Cell Factories, 2012
Background The expression and activity of the different Saccharomyces cerevisiae hexose uptake systems (Hxt) and the kinetics of glucose uptake are considered essential to industrial alcoholic fermentation performance.
Palma Margarida, Madeira Sara, Mendes-Ferreira Ana, Sá-Correia Isabel   +3 more
doaj   +1 more source

GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers [PDF]

, 2012
Background: Increased glycolytic activity is a hallmark of cancer, allowing staging and restaging with 18F-fluorodeoxyglucose-positron-emission-tomography (PET).
Agostinelli, Claudio, Bergmann, Lothar, Diener, Jürgen, Döring, Claudia, Fanti, Stefano, Gallamini, Andrea, Hansmann, Martin-Leo, Hartmann, Sylvia, Pileri, Stefano, Zinzani, Pier Luigi   +9 more
core   +1 more source

Myostatin regulates glucose uptake in BeWo cells [PDF]

American Journal of Physiology-Endocrinology and Metabolism, 2007
Myostatin is a member of the transforming growth factor (TGF)-β superfamily, known for its ability to inhibit muscle growth. It can also regulate metabolism and glucose uptake in a number of tissues. To determine the mechanism of myostatin's effect on glucose uptake, we evaluated its actions using choriocarcinoma cell lines that are widely used as ...
Antony, Nisha, Bass, John J., McMahon, Christopher D., Mitchell, Murray D.   +3 more
openaire   +3 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Involvement of atypical protein kinase C in the regulation of cardiac glucose and long-chain fatty acid uptake

Frontiers in Physiology, 2012
Aim: The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/ long-chain fatty acid uptake are not fully understood.
Daphna D.J. Habets, Joost J.F.P. Luiken, Margriet eOuwens, Will A. Coumans, Monique eVergouwe, Stine J. Maarbjerg, Michael eLeitges, Arend eBonen, Erik A. Richter, Jan eGlatz   +9 more
doaj   +1 more source

Constitutively Active CaMKKα Stimulates Skeletal Muscle Glucose Uptake in Insulin-Resistant Mice In Vivo [PDF]

, 2013
In insulin-sensitive skeletal muscle, the expression of constitutively active Ca(2+)/calmodulin-dependent protein kinase kinase α (caCaMKKα) stimulates glucose uptake independent of insulin signaling (i.e., Akt and Akt-dependent TBC1D1/TBC1D4 ...
Beck Jorgensen, Bjornholm, C. A. S. Smith, C. A. Witczak, DeFronzo, Enslen, Ferr  , J. J. Brault, J. L. Ferey, J. M. Hinkley, Kennedy, Kramer, L. A. A. Gilliam, Surwit, Surwit, Towbin, Treebak, Vichaiwong, Wright, Yano   +19 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source