Metabolic and transcriptomic analysis of Huntington's disease model reveal changes in intracellular glucose levels and related genes. [PDF]
Huntington's Disease (HD) is a neurodegenerative disorder caused by an expansion in a CAG-tri-nucleotide repeat that introduces a poly-glutamine stretch into the huntingtin protein (mHTT).
Chaves, Gepoliano+6 more
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The metabolism of the oral flora. 1. The oxygen uptake and acid production by mixed human saliva in the presence and absence of glucose [PDF]
R.L. Hartles, Norma D. McDonald
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A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Adrenaline action in normal and insulin-resistant Zucker rat skeletal muscles : Effect on insulin-stimulated glucose uptake and glycogen breakdown [PDF]
Carbohydrates are the major source of energy for most humans and account for about 60% of the energy consumed. In the human body carbohydrates are stored as glycogen in the liver and in the skeletal muscles.
Alhaj, Nader Ibrahim Mahmoud
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A CONTINUOUS FLOW METHOD FOR THE DETERMINATION OF GLUCOSE UPTAKE BY EXCISED RAT DIAPHRAGM [PDF]
G. R. Williams
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The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley +1 more source
Regulation of injury-induced skeletal myofiber regeneration by glucose transporter 4 (GLUT4)
Background Insulin resistance and type 2 diabetes impair cellular regeneration in multiple tissues including skeletal muscle. The molecular basis for this impairment is largely unknown.
Tyler J. Sermersheim+5 more
doaj +1 more source
Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou+2 more
wiley +1 more source
Objective: Skeletal muscle is an attractive target for blood glucose-lowering pharmacological interventions. Oral dosing of small molecule direct pan-activators of AMPK that bind to the allosteric drug and metabolite (ADaM) site, lowers blood glucose ...
Nicolas O. Jørgensen+10 more
doaj
The effect of vitamin : a deficiency on glucose uptake in the rat
This thesis describes an investigation of the effects of vitamin A deficiency on gut function, The central hypothesis to be tested was that acute vitamin A deficiency affects glucose uptake from the small intestine- The hypothesis was tested using a ...
Oenzil, Fadil.
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