Results 311 to 320 of about 680,023 (357)
Some of the next articles are maybe not open access.
Osmotic Regulation of Cellular Glucose Uptake
2007This chapter describes various approaches allowing the study of hyperosmolarity in the functions of 3T3-L1 adipocytes. Hyperosmolarity mimics insulin responses, such as glucose uptake and membrane ruffling, but also antagonizes these insulin effects, which can be evaluated in 3T3-L1 adipocytes.
Gual, Philippe +6 more
openaire +4 more sources
Ca2+ and insulin-mediated glucose uptake
Current Opinion in Pharmacology, 2008Insulin stimulates glucose uptake in striated muscle and fat via a complex cascade of signaling events. Insulin resistance in these tissues and type 2 diabetes constitute major and rapidly increasing health problems in society. Recent research implicates an important role of Ca(2+) in insulin-mediated glucose uptake. Maneuvers that increase or decrease
Johanna T, Lanner +3 more
openaire +2 more sources
C&EN Global Enterprise, 2019
The methods typically used for studying glucose metabolism in living systems, such as positron-emission tomography (PET) and fluorescence imaging, have drawbacks. PET is expensive and requires radioactive reagents with short half-lives. Fluorescence methods can suffer from high background and low tissue penetration.
openaire +1 more source
The methods typically used for studying glucose metabolism in living systems, such as positron-emission tomography (PET) and fluorescence imaging, have drawbacks. PET is expensive and requires radioactive reagents with short half-lives. Fluorescence methods can suffer from high background and low tissue penetration.
openaire +1 more source
Cause of glucose oscillations during glucose infusion: periodic variation in glucose uptake
American Journal of Physiology-Endocrinology and Metabolism, 1980Constant infusion of glucose (10 mg . kg-1 . min-1) into conscious, intact dogs induced oscillations in the plasma concentrations of glucose and insulin. Glucose rose from basal (98 +/- 1 mg/dl) and, after 3 h, entered oscillations that persisted until the end of the 9-h glucose infusion.
C R, Bowden, R N, Bergman, D J, Marsh
openaire +2 more sources
Glucose Uptake and Production During the Oral Glucose Tolerance Test
Diabetes, 1968During the three hours required for absorption of most of a U-C-14-glucose load (1 gm./kg.) given orally to an intact unanesthetized dog in the postabsorptive state, about three quarters of the load reaches the peripheral circulation. The absence of randomization of the label, seen when an equal oral load of 6-C-14-glucose is given, indicates that the ...
R, Steele +3 more
openaire +2 more sources
Forearm glucose uptake during glucose tolerance tests in chronic alcoholics
Scandinavian Journal of Clinical and Laboratory Investigation, 1977In twelve chronic alcoholics the glucose uptake in a forearm segment was studied during glucose tolerance tests. The tests were performed twice in each case, on the 3rd and on the 10th to 14th days after admission to hospital in an intoxicated state after a period of excessive alcohol intake.
R, Hed +3 more
openaire +2 more sources
GLUCOSE PHOSPHORYLATION AS A BARRIER TO MUSCLE GLUCOSE UPTAKE
Clinical and Experimental Pharmacology and Physiology, 2005SUMMARY1. Glucose phosphorylation is the first irreversible step of the muscle glucose uptake pathway and is catalysed by a hexokinase isozyme.2. While glucose transport is the primary barrier to muscle glucose uptake during basal conditions, glucose phosphorylation becomes an important barrier to muscle glucose uptake during stimulated conditions such
openaire +2 more sources
Science's STKE, 2001
Insulin is essential for proper control of the concentration of glucose in the blood, and failure of insulin signaling contributes to type 2 diabetes mellitus. The insulin receptor produces multiple intracellular signals, however, and it has not been clear which of these are important for regulation of metabolism in liver and muscle and ...
+4 more sources
Insulin is essential for proper control of the concentration of glucose in the blood, and failure of insulin signaling contributes to type 2 diabetes mellitus. The insulin receptor produces multiple intracellular signals, however, and it has not been clear which of these are important for regulation of metabolism in liver and muscle and ...
+4 more sources
Discovery and Optimization of Glucose Uptake Inhibitors
Journal of Medicinal Chemistry, 2020Aerobic glycolysis, originally identified by Warburg as a hallmark of cancer, has recently been implicated in immune cell activation and growth. Glucose, the starting material for glycolysis, is transported through the cellular membrane by a family of glucose transporters (GLUTs). Therefore, targeting glucose transporters to regulate aerobic glycolysis
Kevin G. Liu +10 more
openaire +2 more sources
Energetics of glucose uptake in Salmonella typhimurium
Archives of Microbiology, 1987We have studied the energetics of glucose uptake in Salmonella typhimurium. Strain PP418 transports glucose via the phosphoenolpyruvate: glucose phosphotransferase system, while strain PP1705 lacks this system and can only use the galactose permease for glucose uptake. These two strains were cultured anaerobically in glucose-limited chemostats.
M, Driessen, P W, Postma, K, van Dam
openaire +2 more sources