Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes [PDF]
, 2013 BACKGROUND: Phytanic acid (PA) is a chlorophyll metabolite with potentials in regulating glucose metabolism, as it is a natural ligand of the peroxisome proliferator-activated receptor (PPAR) that is known to regulate hepatic glucose homeostasis.
Che, Brita Ngum +4 more
core +3 more sources
Glucose-targeted niosomes deliver vasoactive intestinal peptide (VIP) to the brain [PDF]
, 2004 The aim of this study was to evaluate glucose-bearing niosomes as a brain targeted delivery system for the vasoactive intestinal peptide (VIP). To this end, VIP/125I-VIP-loaded glucose-bearing niosomes were intravenously injected to mice.
Begley +31 more
core +2 more sources
Chronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats [PDF]
, 2014 Chronic psychological stress is a prominent risk factor involved in the pathogenesis of many complex diseases, including major depression, obesity, and type II diabetes.
Abel +53 more
core +1 more source
Glucose uptake and distribution across the human skeleton using state-of-the-art total-body PET/CT
Bone Research, 2023 A growing number of studies have demonstrated that the skeleton is an endocrine organ that is involved in glucose metabolism and plays a significant role in human glucose homeostasis. However, there is still a limited understanding of the in vivo glucose
Weizhao Lu +4 more
doaj +1 more source
Sensing and uptake of glucose in Saccharomyces cerevisiae [PDF]
Biophysical Journal, 2009 Maintaining diverse cellular activities while consuming enough nutrients to sustain them is an essential task for all organisms. For the budding yeast Saccharomyces cerevisiae, glucose is the preferred sugar that is metabolized and is also a stimulus that controls the expression level of some quarter of the yeast's genes.
Hyun Youk, Alexander van Oudenaarden
openaire +2 more sources
Stable isotope metabolomics of pulmonary artery smooth muscle and endothelial cells in pulmonary hypertension and with TGF-beta treatment. [PDF]
, 2020 Altered metabolism in pulmonary artery smooth muscle cells (PASMCs) and endothelial cells (PAECs) contributes to the pathology of pulmonary hypertension (PH), but changes in substrate uptake and how substrates are utilized have not been fully ...
D' Alessandro, Angelo +12 more
core +1 more source
PLoS ONE, 2022 The fluorescent derivative of glucose, 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)-amino]-D-glucose (2NBDG), is a widely used surrogate reagent to visualize glucose uptake in live cells at single cell resolution. Using CRISPR-Cas9 gene editing in 5TGM1
Lucas J D'Souza +2 more
doaj +1 more source
Myosin 1c: A novel regulator of glucose uptake in brown adipocytes
Molecular Metabolism, 2021 Objective: The potential of brown adipose tissue (BAT) to influence energy homeostasis in animals and humans is encouraging as this tissue can increase fatty acid and glucose utilization to produce heat through uncoupling protein 1 (UCP1), but the actual
Alice Åslund +5 more
doaj
Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]
, 2017 Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash +5 more
core +1 more source
Frontiers in Endocrinology, 2017 Emerging evidence suggests that undercarboxylated osteocalcin (ucOC) improves muscle glucose uptake in rodents. However, whether ucOC can directly increase glucose uptake in both glycolytic and oxidative muscles and the possible mechanisms of action ...
Xuzhu Lin +11 more
doaj +1 more source