Results 31 to 40 of about 680,023 (357)

Decreased basal hepatic glucose uptake in impaired fasting glucose [PDF]

Diabetologia, 2017
This research aimed to define the pathophysiological defects responsible for the elevated fasting plasma glucose (FPG) concentration and excessive rise in post-load plasma glucose observed in individuals with impaired fasting glucose (IFG).We used tracer techniques to quantify basal splanchnic (primarily hepatic) glucose uptake and glucose fluxes ...
Mariam, Alatrach, Christina, Agyin, John, Adams, Ralph A, DeFronzo, Muhammad A, Abdul-Ghani   +4 more
openaire   +2 more sources

Organ-Specific Glucose Uptake: Does Sex Matter?

Cells, 2022
Glucose uptake by peripheral organs is essential for maintaining blood glucose levels within normal range. Impaired glucose uptake is a hallmark of type 2 diabetes (T2D) and metabolic syndrome and is characterized by insulin resistance.
Adithi Gandhi, Ryan Tang, Youngho Seo, Aditi Bhargava   +3 more
doaj   +1 more source

A Rab10:RalA G protein cascade regulates insulin-stimulated glucose uptake in adipocytes. [PDF]

, 2014
Insulin-stimulated glucose uptake in fat and muscle is mediated by the major facilitative glucose transporter Glut4. Insulin controls the trafficking of Glut4 to the plasma membrane via regulation of a series of small G proteins, including RalA and Rab10.
Chen, Xiao-Wei, Karunanithi, Sheelarani, Leto, Dara, Saltiel, Alan R, Sun, Jingxia, Uhm, Maeran, Xiong, Tingting   +6 more
core   +1 more source

Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects. [PDF]

, 2015
We evaluated the hypothesis that lactate shuttling helps support the nutritive needs of injured brains. To that end, we utilized dual isotope tracer [6,6-(2)H2]glucose, that is, D2-glucose, and [3-(13)C]lactate techniques involving arm vein tracer ...
Brooks, George A, Glenn, Thomas C, Horning, Michael A, Hovda, David A, Martin, Neil A, McArthur, David L, Vespa, Paul   +6 more
core   +1 more source

Effects of Oil Palm (Elais guineensis) Fruit Extracts on Glucose Uptake Activity of Muscle, Adipose and Liver Cells

ASEAN Journal on Science and Technology for Development, 2015
The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF
S Faez, H Muhajir, I Amin, A Zainah
doaj   +1 more source

In vitro 2-deoxy-2-[18F]fluoro-D-glucose uptake: practical considerations [PDF]

, 2012
In oncology 2-deoxy-2-[F-18]fluoro-D-glucose ([F-18]-FDG), a glucose analogue, is the most used positron emission tomography (PET) tracer. There are however some limitations due to low metabolic activity or high surrounding physiological uptake in ...
Goethals, Ingeborg, Lambert, Bieke, Mees, Gilles, Mertens, Koen, Van De Wiele, Christophe   +4 more
core   +1 more source

Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

Journal of Pharmacological Sciences, 2011
Activation of Akt by insulin is transmitted via phosphatidylinositol-3-OH kinase (PI-3K) and enhances glucose uptake. The PI-3K/Akt signaling is diminished in insulin resistance.
Shuichiro Yano, Saori Morino-Koga, Tatsuya Kondo, Mary Ann Suico, Tomoaki Koga, Yuichiro Shimauchi, Shingo Matsuyama, Tsuyoshi Shuto, Takashi Sato, Eiichi Araki, Hirofumi Kai   +10 more
doaj   +1 more source

Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]

, 2017
Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash, Corbett, Austin J, Jamshidi, Neema, Palsson, Bernhard O, Thomas, Alex, Zielinski, Daniel C   +5 more
core   +1 more source

Fructose transport-deficient Staphylococcus aureus reveals important role of epithelial glucose transporters in limiting sugar-driven bacterial growth in airway surface liquid. [PDF]

, 2014
Hyperglycaemia as a result of diabetes mellitus or acute illness is associated with increased susceptibility to respiratory infection with Staphylococcus aureus.
A Brennan, A Sheludiakova, A Tamer, AA Pezzulo, AL Brennan, Alex J. McCarthy, AR Manolescu, BJ Philips, BJ Philips, BP Cummings, C Siebold, CA Colville, CA Merlo, CI Cheeseman, Daniela Braun, Deborah L. Baines, DM Wood, E Kupeli, EH Baker, EH Baker, Emma H. Baker, FV Donenko, G Saumon, HL Kornberg, I Knezevic, J Plumbridge, James P. Garnett, Jodi A. Lindsay, JP Garnett, JP Garnett, JP Garnett, JP Garnett, K Seidl, K Seidl, KC Strasters, KK Kalsi, KK Kalsi, KL Stanhope, M Faiyaz-Ul-Haque, Matthew R. Farrant, MM Myerburg, MT Le, ND Meadow, PA Dawson, PD Fey, PM Barker, PN Wahjudi, R Pyla, RJ Lee, SJ Curtis, YC Lee   +50 more
core   +1 more source

Effect of glucose availability on glucose transport in bovine mammary epithelial cells

Animal, 2012
Primary bovine mammary epithelial cells (BMEC) were cultured in media containing varying concentrations of glucose, to determine the effects of glucose availability on glucose transport and its mechanism in bovine mammary gland.
K. Zhao, H.Y. Liu, H.F. Wang, M.M. Zhou, J.X. Liu   +4 more
doaj   +1 more source