Results 51 to 60 of about 632,919 (362)
Methanolic extract of Momordica cymbalaria enhances glucose uptake in L6 myotubes in vitro by up-regulating PPAR-gamma and GLUT-4 [PDF]
, 2014 The present study was undertaken to evaluate the influence of the methanolic fruit extract of Momordica cymbalaria (MFMC) on PPAR gamma (Peroxisome Proliferator Activated Receptor gamma) and GLUT-4 (Glucose transporter-4) with respect to glucose ...
Ashok, G. +4 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Journal of Physical Fitness and Sports MedicineExcess accumulation of visceral fat induces insulin resistance in skeletal muscle and impairs glucose tolerance. Although weight loss improves glucose tolerance by reducing visceral fat mass, the effects of the speed of weight loss on glucose metabolism ...
Yudai Nonaka +4 more
doaj +1 more source
iRADIOLOGY, 2023 Background Brain metastases are frequent complications for lung cancer patients. However, changes in the brain of lung cancer patients have received little attention. We aimed to explore whether alterations in brain glucose uptake and brain texture occur
Xue Xie +7 more
doaj +1 more source
Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. [PDF]
, 2008 OBJECTIVE Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related ...
Caldwell, Charles +13 more
core +2 more sources
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Interplay between glucose and palmitate uptake in breast carcinoma in vitro [PDF]
, 2018 One of the most studied tumor cells lines in vitro is the breast carcinoma MDA-MB-231 cell line. Several studies have proved its glycolytic profile, namely known as the Warburg effect.
Carrillo, Paloma +4 more
core
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles [PDF]
, 2004 The study reports the initial biological evaluation of targeted polymeric glycol chitosan vesicles as carrier systems for doxorubicin (Dox). Transferrin (Tf) was covalently bound to the Dox-loaded palmitoylated glycol chitosan (GCP) vesicles using ...
Couet, William +5 more
core +1 more source
Exercise training-induced PPARβ increases PGC-1α protein stability and improves insulin-induced glucose uptake in rodent muscles [PDF]
, 2020 This study aimed to investigate the long-term effects of training intervention and resting on protein expression and stability of peroxisome proliferator-activated receptor β/δ (PPARβ), peroxisome proliferator-activated receptor gamma coactivator 1-α ...
Holloszy, John O +3 more
core +2 more sources