Results 71 to 80 of about 632,919 (362)

Transendothelial glucose transport is not restricted by extracellular hyperglycaemia [PDF]

, 2016
Endothelial cells are routinely exposed to elevated glucose concentrations post-prandially in healthy individuals and permanently in patients with metabolic syndrome and diabetes, and so we assessed their sugar transport capabilities in response to high ...
Aird, Alpert, Artwohl, Asano, Asano, Asimina Kerimi, Augustin, Barros, Bauer, Bentley, Brownlee, Burgin-Maunder, Calvo, Chen, Cogger, Coughlan, Cucullo, Culic, De Bock, Debosch, Doddaballapur, Durand, Elfeber, Ellinsworth, Galley, Gary Williamson, Gerritsen, Giacco, Giugliano, Gould, Guo, Huang, Huang, Huggett, Ido, Karen E. Porter, Khayat, Kim, Krutzfeldt, McDonough, McGinn, Medina, Michel, Mimura, Montecinos, Mueckler, Nolan, Ohtsubo, Ohtsuki, Pardridge, Peters, Pouliot, Pujol-Gimenez, Purcell, Qi, Rajah, Rajendran, Rungaldier, Sajja, Sarka Tumova, Scheepers, Shah, Simpson, Stan, Sukriti, Szablewski, Szewczyk, Tajes, Torimoto, Vandekeere, Varma, Verdegem, Vrhovac, Wang, Warboys, Wegner, Weisova, Wilson-O'Brien, Wisse, Ying, Zhu, Ziegler   +81 more
core   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH Kinase (PI-3K) / Akt Pathway

Journal of Pharmacological Sciences, 2011
Activation of Akt by insulin is transmitted via phosphatidylinositol-3-OH kinase (PI-3K) and enhances glucose uptake. The PI-3K/Akt signaling is diminished in insulin resistance.
Shuichiro Yano, Saori Morino-Koga, Tatsuya Kondo, Mary Ann Suico, Tomoaki Koga, Yuichiro Shimauchi, Shingo Matsuyama, Tsuyoshi Shuto, Takashi Sato, Eiichi Araki, Hirofumi Kai   +10 more
doaj  

Impact of assimilable nitrogen availability in glucose uptake kinetics in Saccharomyces cerevisiae during alcoholic fermentation

Microbial Cell Factories, 2012
Background The expression and activity of the different Saccharomyces cerevisiae hexose uptake systems (Hxt) and the kinetics of glucose uptake are considered essential to industrial alcoholic fermentation performance.
Palma Margarida, Madeira Sara, Mendes-Ferreira Ana, Sá-Correia Isabel   +3 more
doaj   +1 more source

High glucose up-regulates ENaC and SGK1 expression in HCD-cells [PDF]

, 2006
Background/Aim: Diabetic nephropathy is associated with progressive renal damage, leading to impaired function and end-stage renal failure. Secondary hypertension stems from a deranged ability of cells within the kidney to resolve and appropriately ...
Bell LM, Bhargava A, Bland R, Christensen O, Claire Hills, Demerdash TM, Di Paolo S, Hoffman BB, Hong-Long JI, Jeanette Bennett, Khan ZA, Lang F, Lee CT, Lindschau C, Loffing J, Marshall SM, Paul Squires, Pierre Ronco, Prie D, Ricci C, Rosemary Bland, Rossier, Satlin LM, Sharma K, Symonian M, Urbach V, Waldegger S, Wang J, Weigert C, Whiteside CI, Yung S   +30 more
core   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

E4orf1: a novel ligand that improves glucose disposal in cell culture.

PLoS ONE, 2011
Reducing dietary fat intake and excess adiposity, the cornerstones of behavioral treatment of insulin resistance (IR), are marginally successful over the long term.
Emily J Dhurandhar, Olga Dubuisson, Nazar Mashtalir, Rashmi Krishnapuram, Vijay Hegde, Nikhil V Dhurandhar   +5 more
doaj   +1 more source

AMP-activated protein kinase plays an important evolutionary conserved role in the regulation of glucose metabolism in fish skeletal muscle cells. [PDF]

PLoS ONE, 2012
AMPK, a master metabolic switch, mediates the observed increase of glucose uptake in locomotory muscle of mammals during exercise. AMPK is activated by changes in the intracellular AMP:ATP ratio when ATP consumption is stimulated by contractile activity ...
Leonardo J Magnoni, Yoryia Vraskou, Arjan P Palstra, Josep V Planas   +3 more
doaj   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Involvement of atypical protein kinase C in the regulation of cardiac glucose and long-chain fatty acid uptake

Frontiers in Physiology, 2012
Aim: The signaling pathways involved in the regulation of cardiac GLUT4 translocation/glucose uptake and CD36 translocation/ long-chain fatty acid uptake are not fully understood.
Daphna D.J. Habets, Joost J.F.P. Luiken, Margriet eOuwens, Will A. Coumans, Monique eVergouwe, Stine J. Maarbjerg, Michael eLeitges, Arend eBonen, Erik A. Richter, Jan eGlatz   +9 more
doaj   +1 more source