Results 31 to 40 of about 3,011 (175)

Investigação genético-epidemiológica e molecular da deficiência de G-6-PD em uma comunidade brasileira G-6-PD deficiency in a Brazilian community: an investigation involving epidemiological genetics and molecular techniques

open access: yesCadernos de Saúde Pública, 2000
Este trabalho teve por objetivo estudar a deficiência de G-6-PD em uma comunidade do interior do Estado de São Paulo (Bragança Paulista). Durante 36 meses foram selecionados 4.621 doadores de sangue do sexo masculino, detectando-se 80 deficientes em G-6 ...
Mariane B. Compri   +2 more
doaj   +1 more source

Positive selection in glycolysis among Australasian stick insects [PDF]

open access: yes, 2013
Background: The glycolytic pathway is central to cellular energy production. Selection on individual enzymes within glycolysis, particularly phosphoglucose isomerase (Pgi), has been associated with metabolic performance in numerous organisms ...
Buckley, T.R.   +5 more
core   +1 more source

PGD: Shared gene linking polycystic ovary syndrome and endometrial cancer, influencing proliferation and migration through glycometabolism

open access: yesCancer Science, Volume 115, Issue 9, Page 2908-2922, September 2024.
PGD is a differentially expressed gene shared between polycystic ovary syndrome and endometrial cancer that modulates endometrial cancer cell proliferation and migration through carbon metabolism. Abstract The relationship among polycystic ovary syndrome (PCOS), endometrial cancer (EC), and glycometabolism remains unclear.
Jia‐ming Chen   +9 more
wiley   +1 more source

Cytotoxicity and toxicoproteomics analysis of thiazolidinedione exposure in human‐derived cardiomyocytes

open access: yesJournal of Applied Toxicology, Volume 44, Issue 8, Page 1214-1235, August 2024.
Abstract Thiazolidinediones (TZDs) (e.g. pioglitazone and rosiglitazone), known insulin sensitiser agents for type II diabetes mellitus, exhibit controversial effects on cardiac tissue. Despite consensus on their association with increased heart failure risk, limiting TZD use in diabetes management, the underlying mechanisms remain uncharacterised ...
Abdullah Al Sultan   +2 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. [PDF]

open access: yes, 2014
The pentose phosphate pathway (PPP) is a fundamental component of cellular metabolism. The PPP is important to maintain carbon homoeostasis, to provide precursors for nucleotide and amino acid biosynthesis, to provide reducing molecules for anabolism ...
Breitenbach, Michael   +14 more
core   +5 more sources

Frequent and recent retrotransposition of orthologous genes plays a role in the evolution of sperm glycolytic enzymes [PDF]

open access: yes, 2010
Background The central metabolic pathway of glycolysis converts glucose to pyruvate, with the net production of 2 ATP and 2 NADH per glucose molecule.
Deborah A O'Brien   +2 more
core   +2 more sources

Scrub Typhus Infection Precipitating Hemolysis in a Patient With G6PD Deficiency: A Case Report

open access: yesClinical Case Reports
Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is a well‐known red blood cell enzymopathy and a cause of intravascular hemolysis. This case report presents a child with underlying G6PD deficiency who experienced an acute episode of extensive ...
Ravi Shukla   +5 more
doaj   +1 more source

Origins of a cyanobacterial 6-phosphogluconate dehydrogenase in plastid-lacking eukaryotes [PDF]

open access: yes, 2008
BackgroundPlastids have inherited their own genomes from a single cyanobacterial ancestor, but the majority of cyanobacterial genes, once retained in the ancestral plastid genome, have been lost or transferred into the eukaryotic host nuclear genome via ...
ISEKI Mineo   +5 more
core   +3 more sources

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