A putative glucose 6-phosphate isomerase has pleiotropic functions on virulence and other mechanisms in Acidovorax citrulli [PDF]
Acidovorax citrulli (Ac) is a causal agent of watermelon bacterial fruit blotch (BFB) disease. Because resistance cultivars/lines have not yet been developed, it is imperative to elucidate Ac’s virulence factors and their mechanisms to develop resistant ...
Lynn Heo +5 more
doaj +4 more sources
Clinical and Molecular Spectrum of Glucose-6-Phosphate Isomerase Deficiency. Report of 12 New Cases [PDF]
Glucose-6-phosphate isomerase (GPI, EC 5.3.1.9) is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate, the second reaction step of glycolysis.
Elisa Fermo +11 more
doaj +4 more sources
Case report: Glucose 6-phosphate-isomerase deficiency combine with avascular necrosis of bilateral femoral head [PDF]
BackgroundGlucose 6-phosphate-isomerase deficiency (GPI) is an uncommon autosomal recessive genetic disorder characterized by chronic asphoric hemolytic anemia, jaundice, and hepatospleenomegaly of varying degrees.
Zhenqi Song +6 more
doaj +2 more sources
Value of serum glucose-6-phosphate isomerase in patients with rheumatoid arthritis and correlation with disease activity: A case–control study [PDF]
BACKGROUND: Rheumatoid arthritis (RA) is a common multisystemic autoimmune disease with peripheral joint involvement. Many autoantibodies have been introduced in the course of RA; some of them have diagnostic and prognostic value.
Neda Soleimani +2 more
doaj +2 more sources
Hereditary nonspherocytic hemolytic anemia caused by glucose-6-phosphate isomerase (GPI) deficiency in a Chinese patient: a case report [PDF]
Background Glucose phosphate isomerase (GPI) deficiency is a rare autosomal recessive disorder that causes hereditary nonspherocytic hemolytic anemia (HNSHA).
Yumei Zu +3 more
doaj +2 more sources
Discovery of ebselen as an inhibitor of Cryptosporidium parvum glucose-6-phosphate isomerase (CpGPI) by high-throughput screening of existing drugs [PDF]
Cryptosporidium parvum is a water-borne and food-borne apicomplexan pathogen. It is one of the top four diarrheal-causing pathogens in children under the age of five in developing countries, and an opportunistic pathogen in immunocompromised individuals.
Rana Eltahan +4 more
doaj +2 more sources
Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer [PDF]
Yu-Teng Ma,1,2 Xiao-Fang Xing,1 Bin Dong,3 Xiao-Jing Cheng,1 Ting Guo,1 Hong Du,1 Xian-Zi Wen,1 Jia-Fu Ji1,2 1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research
Ma YT +7 more
doaj +2 more sources
Glucose-6-phosphate isomerase deficiency hemolysis [PDF]
Huang, Bowen +6 more
openaire +3 more sources
Glucose-6-phosphate isomerase deficiency
Most of the metabolic needs of erythrocytes are covered by glycolysis, the oxidative pentose phosphate pathway and the glutathione cycle. Hereditary enzyme deficiencies of all these pathways have been identified, among which glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent erythroenzymopathy in glycolysis, being associated ...
M Lakomek
exaly +4 more sources
Phylogenetic analysis of the glucose-6-phosphate isomerase gene in Trypanosoma cruzi
Trypanosoma cruzi, the agent of Chagas disease, has a basically clonal population structure with rare hybridization events. The species is subdivided into six "Discrete Typing Units" called DTUs I, IIa-e, distributed into two major phylogenetic lineages, T. cruzi I and II (TC I and II).
Michel Tibayrenc +2 more
exaly +4 more sources

