Results 191 to 200 of about 38,854 (228)
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Cytochemical Localization of β-Glucuronidase
Nature, 1950APPLYING histochemical techniques devised by Friedenwald and Becker1, it was found2 that in normal male mouse liver (Fig. 1) and kidney, β-glucuronidase activity is mainly confined to the mitochondria. It was considered that the rise in glucuronidase activity shown by biochemical methods to occur in these organs when repair has commenced subsequent to ...
J G, CAMPBELL, G A, LEVVY
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American Journal of Diseases of Children, 1985
We studied two cases of beta-glucuronidase deficiency. One patient's disease was present at birth and the other patient's disease appeared in early childhood. The symptoms observed in both patients, although of differing severity, included peculiar facies, cloudy cornea, hepatosplenomegaly, hernia, kyphosis, recurrent infections, short stature, and ...
J E, Lee +3 more
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We studied two cases of beta-glucuronidase deficiency. One patient's disease was present at birth and the other patient's disease appeared in early childhood. The symptoms observed in both patients, although of differing severity, included peculiar facies, cloudy cornea, hepatosplenomegaly, hernia, kyphosis, recurrent infections, short stature, and ...
J E, Lee +3 more
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Genetic control of glucuronidase in mice
Biochemical Genetics, 1970Two electrophoretically distinct components of glucuronidase have been resolved in extracts of murine liver. A mutation which results in a ten-fold reduction in liver glucuronidase activity leads to a reduction in intensity of both components. Since the substrate dependencies of both mutant (gg) and wild-type (GG) glucuronidase have previously been ...
Ganschow, R E, Bunker, B G
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The molecular genetics of mammalian glucuronidase
Journal of Cellular Physiology, 1975The genetic factors known to be involved in the final realization of beta-glucuronidase activity in mice are considered from the standpoint of structural genes determining the catalytic activity of enzyme molecules as well as the recognition features of enzyme molecules that identify them for subsequent processing by the cell; processing genes ...
Paigen, K +3 more
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β-Glucuronidase and Tissue Damage
Nature, 1947After repeated feeding of menthol to mice, Fishman1 obtained results which on statistical examination showed an increase in β-glucuronidase in liver, spleen and kidney as compared with organs from untreated animals. Similar results were obtained in dogs fed with borneol.
L M H, KERR, G A, LEVVY
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Genetic Regulation of Mammalian Glucuronidase
1978Publisher Summary Glucuronidase is useful in dividing mutations into four categories: structural genes, regulatory genes, processing genes, and temporal genes. This chapter discusses regulatory genes that affect the synthesis of mouse kidney glucuronidase in response to androgens.
Swank, R T +8 more
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The histochemical localization of glucuronidase
Journal of Cellular and Comparative Physiology, 1948J S, FRIEDENWALD, B, BECKER
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