Results 151 to 160 of about 465,354 (232)

Endovascular and percutaneous embolization of hepatic artery pseudoaneurysm: Etiology, embolic agents and technical success, and experience from a single center. [PDF]

Ann Hepatobiliary Pancreat Surg
Bhujade HV, Sethi A, Nag AK, Gorsi U, Maru S, Irrinki S, Kalra N, Kang M, Kaman L.   +8 more
europepmc   +1 more source

Conservative management of gastric ulcer penetration using a polyglycolic acid sheet: a case report. [PDF]

Endoscopy
Wakatsuki T, Go T, Harada J, Numoto H, Nanimoto Y, Sato T.   +5 more
europepmc   +1 more source

Clues for glues: from serendipity to nature's blueprints in degrader discovery. [PDF]

Essays Biochem
Kozicka Z.
europepmc   +1 more source

Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue

Nature Biomedical Engineering, 2021
Hyunwoo Yuk, Jingjing Wu, Xinyu Mao
exaly   +2 more sources

Chasing molecular glue degraders: screening approaches

Chemical Society Reviews, 2022
Protein-protein interactions (PPIs) govern all biological processes. Some small molecules modulate PPIs through induced protein proximity. In particular, molecular glue degraders are monovalent compounds that orchestrate interactions between a target ...
Ana Domostegui, Luis Nieto Barrado, Carles Perez Lopez   +2 more
exaly   +2 more sources

Ultra-strong bio-glue from genetically engineered polypeptides

Nature Communications, 2021
The development of biomedical glues is an important, yet challenging task as seemingly mutually exclusive properties need to be combined in one material, i.e. strong adhesion and adaption to remodeling processes in healing tissue.
Chao, Jing Sun, Li Xiang
exaly   +2 more sources

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

Nature, 2020
Molecular glue compounds induce protein–protein interactions that, in the context of a ubiquitin ligase, lead to protein degradation1. Unlike traditional enzyme inhibitors, these molecular glue degraders act substoichiometrically to catalyse the rapid ...
Mikołaj Michal Słabicki, Zuzanna Kozicka, Georg Petzold   +2 more
exaly   +2 more sources

Rational discovery of molecular glue degraders via scalable chemical profiling

Nature Chemical Biology, 2020
Cristina Mayor-Ruiz, Zuzanna Kozicka, Hana Imrichova   +2 more
exaly   +2 more sources

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Molecular Glue Discovery: Current and Future Approaches.

Journal of Medicinal Chemistry, 2023
The intracellular interactions of biomolecules can be maneuvered to redirect signaling, reprogram the cell cycle, or decrease infectivity using only a few dozen atoms.
Jeffrey A. Dewey, C. Delalande, S. Azizi, V. Lu, D. Antonopoulos, G. Babnigg   +5 more
semanticscholar   +1 more source