Glutamate Receptor Agonists as Triggers of Neurotoxicity: Decoding Pathways of Five Neurotoxins and Potential Therapeutic Targets. [PDF]
Turcatel GA, Moura S.
europepmc +1 more source
Annexin A5 Protects SH-SY5Y Cells against L-Glutamate-Induced Cytotoxicity. [PDF]
Abedini Z, Mehdieh M, Takhshid MA.
europepmc +1 more source
Interplay Among Synaptic Glutamate Release and Excitotoxicity: Neuronal Damage and Graphene-Based Materials Related Protection. [PDF]
Cellot G, Ballerini L.
europepmc +1 more source
Design and Antischizophrenic Studies of 1,3-disubstituted Chalcone Derivatives: <i>In-silico</i> Molecular Docking Approach. [PDF]
Zubair AO +4 more
europepmc +1 more source
Monosodium glutamate is associated with dose-dependent reproductive toxicity and sperm dysfunction in male wistar rats. [PDF]
Fasasi OA +4 more
europepmc +1 more source
Quantitative neurotoxic effects of heavy metals and glutamate in mouse hippocampal neuronal cells. [PDF]
Jamsranjav A +6 more
europepmc +1 more source
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Aripiprazole protects cortical neurons from glutamate toxicity.
European Journal of Pharmacology, 2011Neurodegeneration is thought to be a component of schizophrenia pathology, and some antipsychotics appear to slow degenerative changes in patients. Aripiprazole, the first partial dopamine D(2) receptor agonist approved for the treatment of schizophrenia, is suggested to be neuroprotective based on non-clinical studies using transformed cell lines and ...
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Astrocytic phospholipase A2 contributes to neuronal glutamate toxicity.
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Smoothened is a therapeutic target for reducing glutamate toxicity in ischemic stroke
Science Translational Medicine, 2021Description Activation of SHH pathway contributes to glutamate toxicity, and inhibition of SMO reduces ischemic brain damage in mice and monkeys. A smooth-ened approach for ischemia One of the consequences of brain ischemia is the release of glutamate ...
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