Results 161 to 170 of about 154,786 (259)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

N-Acetyl-Aspartyl Glutamic Acid (NAAGA)-Based Eye Drops for Contact Lens Wearers with Dry Eye Symptoms and Discomfort. [PDF]

Vision (Basel)
Misheva I, Daskalov V, Dzhelebov D, Ilieva K, Kermedchieva R, Topchiyska M, Yanev P, Grupcheva C.   +7 more
europepmc   +1 more source

Engineering Crosslinker‐Free Sericin–Gelatin Hydrogels With Tunable Rheology for 3D Printing Applications

Journal of Polymer Science, EarlyView.
Gelatin derived from porcine tissue and sericin extracted from Bombyx mori cocoons are combined to form crosslinker‐free hydrogels with tunable composition, enabling extrusion‐based 3D printing and biocompatible constructs for biomedical applications. ABSTRACT Hydrogels can be processed by 3D printing to manufacture tailor made structures, broadening ...
André S. Macedo, Alaitz Etxabide, Teresa Carranza, Ricardo Brito‐Pereira, Clarisse Ribeiro, Pedro Guerrero, Koro de la Caba, Senentxu Lanceros‐Méndez   +7 more
wiley   +1 more source

An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations. [PDF]

Nucleic Acids Res
Specht C, Tapia A, Penrod S, Soriano GA, Awawdeh A, Alshawi SA, White CA, Beaudoin JD, Doud EH, Vargas-Rodriguez O, Huang Y, Tharp JM.   +11 more
europepmc   +1 more source

GLUTAMIC ACID DECARBOXYLASE IN BRAIN

Journal of Biological Chemistry, 1951
E, ROBERTS, S, FRANKEL
openaire   +2 more sources

[18F] PSMA PET‐CT and [18F] Choline PET‐CT in the Diagnosis of High‐Risk Localized Prostate Cancer: Comparation of Both Tests

The Prostate, EarlyView.
ABSTRACT Background To compare choline PET‐CT and PSMA PET‐CT in a cohort of patients with high‐risk localized prostate cancer, assessing the diagnostic capacity of both tests. whose therapeutic approach could be modified based on the results. Methods An observational study was conducted in 116 patients with high‐risk prostate cancer between January ...
M. A. Tárraga‐Honrubia, A. S. Salinas‐Sánchez, S. Navarro‐Jiménez, M. V. Lorenzo‐Sánchez, P. Carrión‐López, J. M. Giménez‐Bachs   +5 more
wiley   +1 more source

Glutamic Acid at Position 343 in PB2 Contributes to the Virulence of H1N1 Swine Influenza Virus in Mice. [PDF]

Viruses
Wang Y, Zhong Q, Meng F, Cheng Z, Zhang Y, Song Z, Zhang Y, Feng Z, Zhai Y, Chen Y, Qiao C, Yang H.   +11 more
europepmc   +1 more source

Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47–55

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys, Marco Giulini, Vlad Cojocaru, Anna Engel, Xiaotong Xu, Jorge Roel‐Touris, Cunliang Geng, Francesco Ambrosetti, Brian Jiménez‐García, Zuzana Jandova, Panagiotis I. Koukos, Charlotte van Noort, João M. C. Teixeira, Siri C. van Keulen, Manon Réau, Rodrigo V. Honorato, Alexandre M. J. J. Bonvin   +16 more
wiley   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Letter to the Editor in response to the article "Prediction of future insulin deficiency in glutamic acid decarboxylase autoantibody enzyme-linked immunosorbent assay-positive patients with slowly progressive type 1 diabetes". [PDF]

J Diabetes Investig
Zhao C.
europepmc   +1 more source