Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Reversible Isolated Opsoclonus in a Patient With Gastric Cancer and Antibodies to Glutamic Acid Decarboxylase and Myelin Oligodendrocyte Glycoprotein. [PDF]
CureusBommireddipalli A +6 more
europepmc +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Coculture Corynebacterium glutamicum and Bacillus licheniformis for producing poly-γ-glutamic acid from glucose. [PDF]
Appl Microbiol BiotechnolLiu W +13 more
europepmc +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan +14 more
wiley +1 more source
Fulminant type 1 diabetes with high-titer anti-glutamic acid decarboxylase antibodies: Likely rapid progression from stage 2 to 3. [PDF]
J Diabetes InvestigSato M +6 more
europepmc +1 more source
Exteroceptive Reflexes in Stiff Person Syndrome, Other Neurological Conditions and Healthy Controls
Movement Disorders Clinical Practice, EarlyView.Abstract Background Stiff person syndrome (SPS) is a rare disabling neurological condition with overlapping symptomatology with more common neurological conditions. Exaggerated exteroceptive reflex mechanisms are thought to play a role in its pathophysiology.
Belinda Cruse +8 more
wiley +1 more source
Oculomotor Abnormalities in Anti-Glutamic Acid Decarboxylase-Positive Stiff Person Syndrome. [PDF]
Neurol IntSkacik P +6 more
europepmc +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
wiley +1 more source
Role of aspartic acid and glutamic acid in dentin remineralization: A systematic review of emerging therapeutic approaches. [PDF]
J Conserv Dent EndodKrishnan A +3 more
europepmc +1 more source