Results 191 to 200 of about 283,316 (308)

Umami induces pulmonary epithelial senescence via L-glutamic acid-triggered minority MOMP. [PDF]

NPJ Sci Food
Zhang J, Zhao Y, Yang B, He Q, Luo P, Gao Z.   +5 more
europepmc   +1 more source

Synergistic Effects of Salinization and Artificial Root Exudates on Soil Phosphatase Activity in Coastal Soil

Land Degradation &Development, EarlyView.
ABSTRACT Coastal soil salinization from rising seawater levels has adverse impacts on soil function, seed germination, and plant growth. Root exudates play a key role in supporting microbial activity, nutrient cycling, and plant health, yet little is known about the combined effects of salinization and the addition of artificial root exudates (AREs) on
Nicolina Lentine, Sarah E. Krisak, Dirk W. Vanderklein, Matthew S. Schuler, Nina M. Goodey   +4 more
wiley   +1 more source

Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs. [PDF]

J Clin Invest
Wang X, Sun H, Tan Y, Xu S, Liu Z, Ji K, Qiu D, Deng J, Feng B, Wu X, Iwakura Y, Chen M, Feng R, Huang C, Tang C.   +14 more
europepmc   +1 more source

Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats

Lipids, EarlyView.
ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa, Jaiurte Gomes Martins da Silva, Érique Ricardo Alves, Laís Caroline da Silva Santos, Bruno José do Nascimento, Marcelle Mariana Sales de França, Vanessa Bischoff Medina, Ismaela Maria Ferreira de Melo, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +9 more
wiley   +1 more source

Molecular Design in l-Glutamic Acid-Based Peptide Assembly Dynamics Driven by Carbodiimide-Fueled Reaction Cycle. [PDF]

Biomacromolecules
Özbek N, Chen X, Kriebisch BAK, Fernández-de-la-Pradilla A, Świderek K, Boekhoven J, Escuder B.   +6 more
europepmc   +1 more source

Poly(O‐Propargyl‐N‐Amino Carbamate), a Reactive Polymer to Underpin Biomedical Applications of Poly(acetylene)s

Macromolecular Rapid Communications, EarlyView.
We report here a new methodology to prepare functional poly(acetylene)s under aqueous conditions. This methodology is underpinned by poly(O‐propargyl‐N‐amino carbamate) (P1), a reactive poly(acetylene) carrying acyl hydrazines. Thus, P1 reacts with aldehydes to give functional poly(acetylene)s, including cationic, hydrophobic, and sugar‐loaded poly ...
Tom Leigh, Greta Bellio, Daniel Crisan, Amit Deb, Alba Ramil‐Bouzas, Andrey Romanyuk, Ivan Torreiro‐Leon, Ana Rey‐Rico, Paco Fernandez‐Trillo   +8 more
wiley   +1 more source

Antimicrobial Proteinoid Nanostructures via Thermal Condensation of L-Glutamic Acid and L-Tyrosine. [PDF]

Nanomaterials (Basel)
Cadeddu M, Adams JRG, La Ragione R, Whelligan DK, Stolojan V, Bernardi N, Smyrnias I, Poddesu B, Cugia G, De Forni D, Malfatti L, Carboni D, Pinna A, Innocenzi P.   +13 more
europepmc   +1 more source

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Accuracy of glutamic acid decarboxylase antibodies for the identification of adult-onset type 1 diabetes mellitus: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Shao MM, Scheideman AF, Zhou AM, Kohn MA, DiMeglio LA, Quandt Z, Speake C, Ho CN, Klonoff DC.   +8 more
europepmc   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source