Results 241 to 250 of about 283,316 (308)

Redox‐responsive dual‐drug nanomedicine integrating cisplatin and trypsin for synergistic reversal of tumor chemoresistance

Smart Molecules, EarlyView.
This study presents a novel glutathione‐activatable prodrug nanomedicine (cRGD‐PEG‐PGlu‐NP (ssTrypsin & CDDP)) that co‐encapsulates cisplatin and a masked protease to combat cisplatin resistance. The dual‐drug system selectively targets resistant tumor cells, enhancing the efficacy of cisplatin while minimizing systemic toxicity.
Xiaolan Yin, Qi Wang, Ming Zhang, Cheng Zhang, Qixian Chen, Haidong Li, Yan Zhao, Yue Wang, Jingyun Wang, Liuwei Zhang, Hongyan Cui   +10 more
wiley   +1 more source

Drug-resistant glutamic acid decarboxylase 65-associated epilepsy: Pre-surgical evaluation and comparison to temporal lobe epilepsy of other etiology. [PDF]

Epilepsia
Thomsen AN, Ortiz-Guerrero G, Dubey D, Britton JW, Smith KM.   +4 more
europepmc   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

The Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato, Kazuki Miura, Juki Nakao, Hiroyuki Nakamura   +3 more
wiley   +1 more source

Comparative study on the effects of glutamic acid and glutamine in promoting intestinal development in chicks through energy metabolism. [PDF]

Anim Biosci
Huang P, Cui Y, Liang W, Zhang L, Tian J, Gan L, Guo L, Chen W, Yang G, Guan J.   +9 more
europepmc   +1 more source

Printing to Fight Antimicrobial Resistance Through Nano/Microstructured Platforms

The Chemical Record, EarlyView.
Additive manufacturing enables the rational design of structured antimicrobial platforms across multiple length scales, from nanofibrous scaffolds and droplet microreactors to 3D and 4D printed constructs. By engineering confinement, interfacial chemistry, and stimuli‐responsive release, these systems exert localized action through complementary ...
Giorgia Puleo, Silvia Orecchio, Dario Savoca, Claudia Pellerito, Vittorio Ferrara, Vincenzo Piscopo, Sebastiano Alberto Fortuna, Alessandra Giardina, Bruno Pignataro, Paola Costanzo, Floriana Campanile, Giuseppe Arrabito   +11 more
wiley   +1 more source

Temporal Lobe Epilepsy Associated With Glutamic Acid Decarboxylase Antibodies: Defining a Distinct Epilepsy Syndrome. [PDF]

Neurol Neuroimmunol Neuroinflamm
Rada A, Reisch LM, Hagemann A, Woermann FG, Bien CG.   +4 more
europepmc   +1 more source

Unlocking molecular dynamics: incorporation of volumetric insights into L-glutamic acid and quaternary ammonium bromides in aqueous medium. [PDF]

BMC Chem
Panda H, Pradhan RK, Das S, Baliarsingh B, Talukdar M, Singh S.   +5 more
europepmc   +1 more source

An engineered glutamic acid tRNA for efficient suppression of pathogenic nonsense mutations. [PDF]

Nucleic Acids Res
Specht C, Tapia A, Penrod S, Soriano GA, Awawdeh A, Alshawi SA, White CA, Beaudoin JD, Doud EH, Vargas-Rodriguez O, Huang Y, Tharp JM.   +11 more
europepmc   +1 more source

Effects of Trehalose, Sodium Hyaluronate and N-Acetyl Aspartyl-Glutamic Acid Artificial Tears on Ocular Surface Parameters in Glaucoma Patients Receiving Preserved and Preservative-Free Prostaglandins. [PDF]

J Clin Med
Martucci A, Quaranta Leoni F, Valentini N, Sorge RP, Mancino R, Aiello F, Cesareo M, Nucci C.   +7 more
europepmc   +1 more source

N-Acetyl-Aspartyl Glutamic Acid (NAAGA)-Based Eye Drops for Contact Lens Wearers with Dry Eye Symptoms and Discomfort. [PDF]

Vision (Basel)
Misheva I, Daskalov V, Dzhelebov D, Ilieva K, Kermedchieva R, Topchiyska M, Yanev P, Grupcheva C.   +7 more
europepmc   +1 more source