Results 211 to 220 of about 24,633 (278)

Effects of deamidation by protein glutaminase on the flavor binding properties of pea protein isolate. [PDF]

Food Chem X
Siripitakpong P, Wongprasert T, Rungrotmongkol T, Suppavorasatit I.   +3 more
europepmc   +1 more source

Targeting the Glutaminolysis Pathway in Glaucoma-Associated Fibrosis. [PDF]

Int J Mol Sci
Kelly Á, Irnaten M, O'Brien C.
europepmc   +1 more source

Pirfenidone Sensitizes Hepatic Stellate Cells to Ferroptosis by Reprogramming Glutamine and Serine Metabolism for GSH Depletion. [PDF]

Antioxidants (Basel)
Li J, Wang L, Li Y, Wang J, Buist-Homan M, Faber KN, Moshage H.   +6 more
europepmc   +1 more source

Expression of Glutamatergic Signaling in Canine Oral Melanocytic Neoplasms. [PDF]

Vet Sci
Masyr A, Pluemhathaikij L, Wang S, Thaiwong-Nebelung T, Smedley RC.   +4 more
europepmc   +1 more source

Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer

Cell Metabolism, 2022
The tumor microenvironment (TME) contains a rich source of nutrients that sustains cell growth and facilitate tumor development. Glucose and glutamine in the TME are essential for the development and activation of effector T cells that exert antitumor ...
Sarah A Best, Ariena Kersbergen, Alexandra L Garnham   +2 more
exaly   +2 more sources

Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

Cell, 2018
SUMMARY Activated T cells differentiate into functional subsets with distinct metabolic programs. Glutaminase (GLS) converts glutamine to glutamate to support the tricarboxylic acid cycle and redox and epigenetic reactions.
Marc O Johnson, Melissa M Wolf, Matthew Z Madden   +2 more
exaly   +2 more sources

Recent Development of Small Molecule Glutaminase Inhibitors

Current Topics in Medicinal Chemistry, 2018
Glutaminase (GLS), which is responsible for the conversion of glutamine to glutamate, plays a vital role in up-regulating cell metabolism for tumor cell growth and is considered to be a valuable therapeutic target for cancer treatment.
Soong-Hyun Kim, Hee-Jong Hwang
exaly   +2 more sources

Phosphate-activated glutaminase expression during tumor development

FEBS Letters, 1994
Changes in phosphate-activated glutaminase activities determined in intact cells and isolated mitochondria have been followed during mouse Ehrlich ascites carcinoma development. Glutaminase activities parallel the levels of poly(A)+ RNAs encoding for the
Juan CARLOS Aledo, Juan A Segura, MIGUEL Angel Medina   +2 more
exaly   +2 more sources