Results 211 to 220 of about 91,004 (324)

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel, Katrin M. Reitmeier, Emilia Kieckhöfer, Khawla Abualia, Duc Nguyen‐Minh, Mahsa Matin, Henning Hagmann, Richard J. M. Coward, Sebastian Brähler, Philipp Antczak, Bernhard Schermer, Thomas Benzing, Patrick Giavalisco, Paul T. Brinkkoetter   +13 more
wiley   +1 more source

Identification and characterization of the glutamine synthetase gene family in oat (<i>Avena sativa</i> L.) and the role of <i>AsGS2-2C</i> under drought stress. [PDF]

Front Plant Sci
Yang M, Zheng S, Li J, Tong S, Zhang M, Cui G, Che C, Zhang W, Wang Y, Zhang T, Teng J, Li B, Yin H.   +12 more
europepmc   +1 more source

Phytotoxicity of aminobisphosphonates targeting both δ¹‐pyrroline‐5‐carboxylate reductase and glutamine synthetase

, 2016
Samuele Giberti, Michele Bertazzini, Mattia Liboni, Łukasz Berlicki, Paweł Kafarski, Giuseppe Forlani   +5 more
openalex   +2 more sources

Characterizing Spatial Associations Between GluCEST MRI and Neurotransmitter Receptor Density in the Human Cortex

Human Brain Mapping, Volume 46, Issue 18, 15 December 2025.
We leveraged in vivo 7T GluCEST MRI and normative PET receptor maps to examine the spatial covariation between cortical glutamate levels and receptor expression. GluCEST signal showed positive spatial associations with NMDA and GABAA, but not mGluR5. These findings enhance our understanding of GluCEST and glutamate‐receptor dynamics across the cortex ...
Maggie K. Pecsok, Golia Shafiei, Ally Atkins, Monica E. Calkins, Ruben C. Gur, Ravi Prakash Reddy Nanga, Ravinder Reddy, Melanie A. Matyi, Jacquelyn Stifelman, Heather Robinson, Erica B. Baller, Russell T. Shinohara, Kosha Ruparel, Kristin A. Linn, Daniel H. Wolf, Theodore D. Satterthwaite, Corey T. McMillan, David Roalf   +17 more
wiley   +1 more source

2-oxoglutarate triggers assembly of active dodecameric <i>Methanosarcina mazei</i> glutamine synthetase. [PDF]

Elife
Herdering E, Reif-Trauttmansdorff T, Kumar A, Habenicht T, Hochberg G, Bohn S, Schuller J, Schmitz RA.   +7 more
europepmc   +1 more source

Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. [PDF]

Int J Med Sci, 2023
Xuan DTM, Wu CC, Wang WJ, Hsu HP, Ta HDK, Anuraga G, Chiao CC, Wang CY.   +7 more
europepmc   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, Volume 12, Issue 45, December 4, 2025.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Subcellular location of chicken brain glutamine synthetase and comparison with chicken liver mitochondrial glutamine synthetase.

, 1983
Darwin Smith, James W. Campbell
openalex   +1 more source

Two Cytosolic Glutamine Synthetase Isoforms of Maize Are Specifically Involved in the Control of Grain Production [PDF]

, 2006
Antoine Martin, Judy Lee, Thomas Kichey, Denise Gerentes, Michel Zivy, Christophe Tatout, Frédéric Dubois, Thierry Balliau, Benoı̂t Valot, Marlène Davanture, Thérèse Tercé‐Laforgue, Isabelle Quilleré, Marie Coque, A. Galláis, María Begoña González‐Moro, Linda Béthencourt, D. Z. Habash, Peter J. Lea, Alain Charcosset, Pascual Pérez, Alain Murigneux, Hitoshi Sakakibara, Stella Hubbart‐Edwards, Bertrand Hirel   +23 more
openalex   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

Advanced Science, Volume 12, Issue 45, December 4, 2025.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan, Miao Han, Mengfei Zhang, Wenbo Chen, Fangde Xie, Xuan Luo, Wenping Wu, Congliang Wang, Donghui Yang, Bin Han, Haijing Zhu, Haisheng Yu, Na Li, Jinlian Hua   +13 more
wiley   +1 more source