Results 221 to 230 of about 91,004 (324)

High‐Throughput Engineering and Modification of Non‐Ribosomal Peptide Synthetases Based on Golden Gate Assembly

Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.
A Golden Gate Assembly (GGA)‐based method was developed for the efficient assembly of natural and engineered non‐ribosomal peptide synthetases (NRPS). This method has enabled the creation of NRPS libraries to generate novel peptides in high‐throughput as well as the targeted derivatisation of natural products (NPs).
Adrian Podolski, Timon A. Lindeboom, Leonard Präve, Maryam Dehghan, Hannah A. Minas, Janik Kranz, Daniel Schindler, Helge B. Bode   +7 more
wiley   +2 more sources

Effective Targeting of Glutamine Synthetase with Amino Acid Analogs as a Novel Therapeutic Approach in Breast Cancer. [PDF]

Int J Mol Sci
Abdelsattar S, Al-Amodi HS, Kamel HF, Al-Eidan AA, Mahfouz MM, El Khashab K, Elshamy AM, Basiouny MS, Khalil MA, Elawdan KA, Elsaka S, Mohamed SE, Khalil H.   +12 more
europepmc   +1 more source

Hepatic glutamine synthetase controls N⁵-methylglutamine in homeostasis and cancer. [PDF]

Nat Chem Biol, 2023
Villar VH, Allega MF, Deshmukh R, Ackermann T, Nakasone MA, Vande Voorde J, Drake TM, Oetjen J, Bloom A, Nixon C, Müller M, May S, Tan EH, Vereecke L, Jans M, Blancke G, Murphy DJ, Huang DT, Lewis DY, Bird TG, Sansom OJ, Blyth K, Sumpton D, Tardito S.   +23 more
europepmc   +1 more source

Review for "CHOK1SV GS‐KO ® SSI Expression System: A combination of the Fer1L4 locus and glutamine synthetase selection"

, 2020

openalex   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, Volume 12, Issue 47, December 18, 2025.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

Predicting hepatocellular carcinoma development in advanced fibrosis or cirrhosis due to chronic hepatitis B: The role of glypican-3, heat shock protein 70, CD34, and glutamine synthetase. [PDF]

Hepatol Forum
Ozturk Y, Purnak T, Simsek H, Sokmensuer C.   +3 more
europepmc   +1 more source

Scanning transmission electron microscopy of submolecular oligomers of stabilized glutamine synthetase from Escherichia coli.

, 1982
Rudy H. Haschemeyer, J.S. Wall, J. F. Hainfeld, Michael R. Maurizi   +3 more
openalex   +1 more source

The role of glutamine synthetase, glutamate synthase and glutamate dehydrogenase in ammonia assimilation by the mycorrhizal fungus Pisolithus tinctorius [PDF]

, 1989
Joanna Kershaw, George R. Stewart
openalex   +1 more source

Influence of Region, Harvest Year, and Variety on Stable Isotope Characterization of Xinjiang Rice From China

AgriFood: Journal of Agricultural Products for Food, Volume 1, Issue 1, Page 21-30, December 2025.
Xinjiang rice isotopic differences were influenced by region, harvest year, variety, with southern rice had more positive δ13C, δ2H and δ18O values than northern. This study provides the first Xinjiang rice traceability data, aiding China's national rice database.
Menglin Zhang, Chunlin Li, Jing Nie, Zhiqiang Zhao, Shengzhi Shao, Yongzhi Zhang, Karyne M. Rogers, Duoyong Zhao, Yuwei Yuan   +8 more
wiley   +1 more source

CitGATA7 interact with histone acetyltransferase CitHAG28 to promote citric acid degradation by regulating the glutamine synthetase pathway in citrus. [PDF]

Mol Hortic
Lin X, Li S, Shi Y, Ma Y, Li Y, Tan H, Zhang B, Xu C, Chen K.   +8 more
europepmc   +1 more source