Results 221 to 230 of about 92,131 (300)

A QSP Model of Valproic Acid Toxicity in Pediatric and Adult Populations: Implications for Formulation Selection and L‐Carnitine Supplementation

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
Schematic workflow of the QSP model development and application. The study builds upon an initial adult male model structure (top left) by integrating reported data on age‐related changes in elimination pathways (top right). This allowed for the extension of the QSP model to pediatric and female populations (bottom right), which was then used to ...
Alejandra Schiavo   +5 more
wiley   +1 more source

Haptoglobin and Glutamine Synthetase May Biomark Cachexia Induced by Antiacute Myeloid Leukaemia Chemotherapy. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Campelj DG   +9 more
europepmc   +1 more source

Bestrophin-2 and glutamine synthetase form a complex for glutamate release. [PDF]

open access: yesNature, 2022
Owji AP   +5 more
europepmc   +1 more source

Compost Tea as a Natural Bioactive Solution: Unlocking the Antimicrobial and Antiviral Potential of Bell Pepper and Citrus Wastes

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Compost teas derived from bell pepper and citrus waste are rich in bioactive phenolics and lignin derivatives, showing strong antibacterial activity against gram‐positive bacteria and potent antiviral effects against HSV‐1 and RSV. These findings highlight their potential as sustainable, circular bioresources for biomedical applications.
Maria Vittoria Verrillo   +7 more
wiley   +1 more source

Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Photocontrol of enzymes with photoswitchable unnatural amino acids hitherto yielded only limited light‐regulation factors (LRFs). Here we boosted the LRF of an imidazole glycerol phosphate synthase variant from ∼15 to ∼100 in a semi‐rational design approach and unraveled the mechanistic fundamentals of this effect via biophysical and computational ...
Sabrina Mandl   +6 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy