Results 231 to 240 of about 92,131 (300)

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, Volume 59, Issue 2, February 2026.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source

2-oxoglutarate triggers assembly of active dodecameric <i>Methanosarcina mazei</i> glutamine synthetase. [PDF]

Elife
Herdering E, Reif-Trauttmansdorff T, Kumar A, Habenicht T, Hochberg G, Bohn S, Schuller J, Schmitz RA.   +7 more
europepmc   +1 more source

A Silencer Element in the First Intron of the Glutamine Synthetase Gene Represses Induction by Glucocorticoids [PDF]

, 2003
Frank Gaunitz, Kerstin Heise, Rolf Gebhardt   +2 more
openalex   +1 more source

Can ammonia scavenging treat MASLD? Evaluating the evidence for L‐ornithine L‐aspartate—A systematic review

European Journal of Clinical Investigation, Volume 56, Issue 2, February 2026.
Abstract Introduction While hyperammonemia is traditionally associated with decompensated cirrhosis, emerging evidence suggests that disturbances in nitrogen homeostasis contribute to disease progression in earlier stages of steatohepatitis and fibrosis.
Abdulrahman Ismaiel, Vera Ciornolutchii, Stefan‐Lucian Popa, Dan L. Dumitrascu   +3 more
wiley   +1 more source

Identification and characterization of the glutamine synthetase gene family in oat (<i>Avena sativa</i> L.) and the role of <i>AsGS2-2C</i> under drought stress. [PDF]

Front Plant Sci
Yang M, Zheng S, Li J, Tong S, Zhang M, Cui G, Che C, Zhang W, Wang Y, Zhang T, Teng J, Li B, Yin H.   +12 more
europepmc   +1 more source

Glutamine synthetase regulates the immune microenvironment and cancer development through the inflammatory pathway. [PDF]

Int J Med Sci, 2023
Xuan DTM, Wu CC, Wang WJ, Hsu HP, Ta HDK, Anuraga G, Chiao CC, Wang CY.   +7 more
europepmc   +1 more source

Extending the diffraction limit of protein crystals: The example of glutamine synthetase from Salmonella typhimurium in the presence of its cofactor ATP [PDF]

, 1993
Shwu Huey Liaw, Gyo Jun, David Eisenberg
openalex   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou, Yitong Lu, Zhaobao Wang, Xiaoqian Du, Bei Jiang, Qiuhui Xuan   +5 more
wiley   +1 more source

Effective Targeting of Glutamine Synthetase with Amino Acid Analogs as a Novel Therapeutic Approach in Breast Cancer. [PDF]

Int J Mol Sci
Abdelsattar S, Al-Amodi HS, Kamel HF, Al-Eidan AA, Mahfouz MM, El Khashab K, Elshamy AM, Basiouny MS, Khalil MA, Elawdan KA, Elsaka S, Mohamed SE, Khalil H.   +12 more
europepmc   +1 more source

GLUTAMINE SYNTHETASE EXPRESSION AND IMMUNOLOCALIZATION IN THE DEVELOPING RAT LUNG. † 1831 [PDF]

, 1996
Vincent G. DeMarco, Daniel Strauss, Vivek B. Shenoy, Marc McCain, Paul Kubilis, Ratna Chakrabarti, Josef Neu   +6 more
openalex   +1 more source