Results 251 to 260 of about 216,468 (357)
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen +14 more
wiley +1 more source
Targeting glutamine synthetase with AS1411-modified exosome-liposome hybrid nanoparticles for inhibition of choroidal neovascularization. [PDF]
Zhang M +7 more
europepmc +1 more source
Phytosulfokine peptide optimizes plant growth and defense via glutamine synthetase GS2 phosphorylation in tomato. [PDF]
Ding S +7 more
europepmc +1 more source
Abstract INTRODUCTION Underlying glutamate dysregulation in Alzheimer's disease can be worsened by environmental factors like manganese (Mn) exposure. This study examined how excess Mn affects glutamatergic signaling and neurotransmission in a beta‐amyloid mouse model. METHODS APP/PSEN1 and control mice were exposed to systemic Mn subcutaneously.
Rebecca A. Buchanan +5 more
wiley +1 more source
Dynamics of glutamine synthetase expression in hepatic ischemia-reperfusion injury: Implications for therapeutic interventions. [PDF]
Huang ZH, Dong MQ, Liu FY, Zhou WJ.
europepmc +1 more source
Structural basis for the helical filament formation of Escherichia coli glutamine synthetase. [PDF]
Huang PC +4 more
europepmc +1 more source
Addendum to “Reconstruction of glutamine synthetase using computer averaging” [PDF]
Joachim Frank +3 more
openalex +1 more source
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu +16 more
wiley +1 more source

