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Glutamine Synthetase: Glial Localization in Brain
Science, 1977Light microscopy immunohistochemical techniques were used to examine the distribution of glutamine synthetase in rat brain. Glutamine synthetase was found to be localized in the glial cells. Neuronal cell bodies, endothelial cells, and choroid epithelium contained no enzyme.
A, Martinez-Hernandez +2 more
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Inhibitors of Glutamine Synthetase
2002Due to the chemical inertness of the N2 molecule, the availability of metabolically accessible inorganic nitrogen sources was a key limiting factor for plant life on earth. The large scale conversion of N2 into NH3 and NO 3 - and their use as nitrogen fertilizer has been an agricultural standard for less than a century.
Guenter Donn, Helmut Köcher
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Glutamine synthetase and transferase
1967This enzyme (or enzymes) catalyzes the following reactions: 1. Glutamate + ATP + NH3 → glutamine + ADP + Pi (glutamine synthesis). 2. Glutamine + NH2OH →γ-glutamylhydroxamate + NH3 (glutamyl transfer reaction). 3. Glutamine + H2O → Glutamate + NH3 (arsenolysis of glutamine).
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Glutamine synthetase and hepatocarcinogenesis
Carcinogenesis, 1995R, Gebhardt, G M, Williams
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Glutamine synthetase activity in Huntington's disease
Life Sciences, 1982Glutamine synthetase activity was measured in seven brain areas post-mortem from control patients, and those with Huntington's disease. The activity of the enzyme was reduced in the frontal and temporal cortex, putamen and cerebellum, but not in the hippocampus, thalamus or olivary nucleus.
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The optical specificity of glutamine synthetase
Archives of Biochemistry and Biophysics, 1960The optical specificity of the glutamine synthetase isolated from dried peas has been studied. The degree of optical specificity shown by the enzyme is a function of the pH, the activating meta-lion concentration, the metal-ion species and the concentration of ammonia or hydroxylamine.
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Glutamine Synthetase from Nocardia corallina
The Journal of Biochemistry, 1971S, Kajinami, E C, Smith
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