Results 301 to 310 of about 216,468 (357)

Gill-specific glutamine synthetase [PDF]

Genome Biology, 2003
openaire   +2 more sources

Repurposing Asparaginase Therapy to Target Cisplatin‐Resistant Cancer Cells

Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT Background Cisplatin and its derivatives remain a cornerstone in the treatment of solid malignancies. Resistance is a major factor limiting their clinical utility. Objectives In the present study, we set out to interrogate therapeutic approaches to target cisplatin‐resistant cancer cells.
Jiantao Wang, Nasim Pouryaghoub, Robert Strauss, Jiri Bartek, Si Min Zhang, Sean G. Rudd   +5 more
wiley   +1 more source

Clustered de novo start-loss variants in GLUL result in a developmental and epileptic encephalopathy via stabilization of glutamine synthetase. [PDF]

Am J Hum Genet
Jones AG, Aquilino M, Tinker RJ, Duncan L, Jenkins Z, Carvill GL, DeWard SJ, Grange DK, Hajianpour MJ, Halliday BJ, Holder-Espinasse M, Horvath J, Maitz S, Nigro V, Morleo M, Paul V, Spencer C, Esterhuizen AI, Polster T, Spano A, Gómez-Lozano I, Kumar A, Poke G, Phillips JA, Underhill HR, Gimenez G, Namba T, Robertson SP.   +27 more
europepmc   +1 more source

Lack of a Regulatory Function for Glutamine Synthetase Protein in the Synthesis of Glutamate Dehydrogenase and Nitrite Reductase in Escherichia coli K12

, 1977
Bernard Newman, Jeff Cole
openalex   +1 more source

The toxic effects of meta‐tyrosine are related to its misincorporation into the proteome and to altered metabolism in cyanobacteria

The FEBS Journal, Volume 292, Issue 20, Page 5439-5456, October 2025.
This study reveals that meta‐tyrosine (m‐Tyr), a nonproteinogenic analog of aromatic amino acids, disrupts protein synthesis and photosynthesis in cyanobacteria by being misincorporated by Phenylalanyl‐tRNA synthetase (PheRS) into essential proteins. Through molecular, biochemical, and proteomic analyses in Synechocystis, the research shows that m‐Tyr ...
Hagit Zer, Roei Matan, David Rasin, Yoram Soroka, Noa Carmi, Hanan Schoffman, Nir Keren, Jörg Nickelsen, Oren Ostersetzer‐Biran   +8 more
wiley   +1 more source

Biocompatible aggregation-induced emission active polyphosphate-manganese nanosheets with glutamine synthetase-like activity in excitotoxic nerve cells. [PDF]

Nat Commun
Wang J, Zhao X, Tao Y, Wang X, Yan L, Yu K, Hsu Y, Chen Y, Zhao J, Huang Y, Wei W.   +10 more
europepmc   +1 more source

Astrocytes as Active Participants in Memory

Journal of Neurochemistry, Volume 169, Issue 10, October 2025.
This review explores how astrocytes support memory by modulating neurotransmitters, interacting with biomolecules, and taking part in synaptic plasticity. We discuss their role across various brain regions and spotlight cutting‐edge methods—such as Ca2+ imaging, optogenetics, chemogenetics, and engram analysis—that have revolutionized our ability to ...
Shay Meron Asher, Inbal Goshen
wiley   +1 more source

Occurrence of glutamine synthetase/glutamate synthase pathway in Gluconobacter suboxydans.

, 1978
Takashi Tachiki, Yoshiharu SHIRASU, Masao Haruna, Tatsurokuro Tochikura   +3 more
openalex   +2 more sources

Serum Proteomic Profile Based on the TGF‐β Pathway Stratifies Risk of Hepatocellular Carcinoma

Liver International, Volume 45, Issue 10, October 2025.
ABSTRACT Background Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related deaths, primarily due to late‐stage diagnosis. In this multicenter study, our goal is to identify functional biomarkers that stratify the risk of HCC in patients with cirrhosis (CP) for early diagnosis.
Xiyan Xiang, Kirti Shetty, Herbert Yu, Bibhuti Mishra, Linda L. Wong, Xianghong Jasmine Zhou, Sanjaya K. Satapathy, James M. Crawford, Patricia S. Latham, Steven‐Huy Han, Brandon Mathew, Nabil N. Dagher, Lawrence Lau, Fellanza Cacaj, Anil K. Vegesna, Srinivasan Dasarathy, Aiwu R. He, Hai Huang, Richard L. Amdur, Lopa Mishra   +19 more
wiley   +1 more source

Post-Traumatic Expressions of Aromatase B, Glutamine Synthetase, and Cystathionine-Beta-Synthase in the Cerebellum of Juvenile Chum Salmon, Oncorhynchus keta. [PDF]

Int J Mol Sci
Pushchina EV, Bykova ME, Varaksin AA.
europepmc   +1 more source