Results 21 to 30 of about 893 (156)

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

SYNTHESIS AND EVALUATION OF SOME ARYLALKENYL AND ARYLEPOXYALKYL HYDROGEN SUCCINATES AND HYDROGEN GLUTARATES AS INHIBITORS OF RAT LIVER β-HYDROXY-β-METHYLGLUTARYL COENZYME A REDUCTASE [PDF]

, 1974
Atherosclerotic disease is an almost universal phenomenon and increases in severity and frequency with increasing age. Atherosclerosis may contribute to several disorders including bursting of an artery, blockage of an artery, or induction of arterial ...
Marecki, Paul Emil
core   +1 more source

Glutaric acidemia type 1 [PDF]

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2006
AbstractGlutaric acidemias comprise different disorders resulting in an increased urinary excretion of glutaric acid. Glutaric acidemia type 1 (GA‐1) is an autosomal recessive disorder of lysine, hydroxylysine, and tryptophan metabolism caused by deficiency of glutaryl‐CoA dehydrogenase.
Gary L, Hedlund, Nicola, Longo, Marzia, Pasquali   +2 more
openaire   +2 more sources

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

GLUTARIC ACIDURIA ‘TYPE II’ [PDF]

Pediatric Research, 1975
A new fetal metabolic disorder is described, mainly characterised by severe acidosis and hypoglycaemia, a' sweaty-feet' like odour, and massive glutaric aciduria and acidaemia. In addition, urinary excretion of isobutyric and isovaleric acid was increased, as well as that of some dicarboxylic acids.
H. Przyrembel, U. Wendel, S. K. Wadman, H. J. Bremer   +3 more
openaire   +1 more source

Anxiety Disorder Types From a Metabolomics Perspective: A Mendelian Randomization Analysis Based on 1400 Plasma Metabolites

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study investigates the causal relationship between plasma metabolites and three common types of anxiety disorders using Mendelian randomization analysis. Our findings propose a novel direction for utilizing metabolites as biomarkers in the diagnosis and treatment of anxiety disorders.
Zhen Xiao, Zedi Wu, Zixin Chen, Ziyue Xu, Qi Zhou, Silan Liu, Muqing Wang, Shujun Hou, Wanling Liu, Zhengyi Li, Kunping Xun, Ning Zhang, Chun Wang   +12 more
wiley   +1 more source

Porous Hexacyanometallate(III) Complexes as Catalysts in the Ring-Opening Copolymerization of CO2 and Propylene Oxide [PDF]

, 2021
In this work, six porous hexacyanometallate complexes (Ni3[Co(CN)6]2, Co3[Co(CN)6]2, Fe3[Co(CN)6]2, Ni3[Fe(CN)6]2, Co3[Fe(CN)6]2, Fe4[Fe(CN)6]2) were synthesized by a complexing agent assisted coprecipitation method and thoroughly characterized via X-ray
González Marcos, María Pilar, González Velasco, Juan Ramón, Penche, Guillermo   +2 more
core   +1 more source

Lueyang Black‐Boned Chicken and Black Bean Soup Promoting the Acute Healing of Skin Wounds, Accompanying Special Flavor Substances

Food Chemistry International, Volume 2, Issue 1, Page 46-57, March 2026.
ABSTRACT Animal protein and plant protein make the protein supplement more comprehensive and further optimize the nutritional structure of the national diet. In this study, a “dual protein” Lueyang black‐boned chicken and black bean soup (FS) was prepared.
Mengya Zhao, Zining Luo, Pengyan Tong, Yining Jia, Xin Yang, Jing Liu, Fangyu Long   +6 more
wiley   +1 more source

Engineering Cyanobacteria for High‐Yield Photosynthetic Isoprene Production With Long‐Term Phenotypic Stability

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1014-1030, March 2026.
Center: Cyanobacterial isoprene production from CO2 and sunlight. Top: CRISPR‐editing for generation of markerless production strains. Top right: Long‐term production assay for strain stability assessment. Bottom right: Engineering of MEP pathway and surrounding metabolism for bottleneck idenfication. Bottom left: Relief of bottleneck by overproduction
Kim N. Janssen, Paul Bolay, Adrian Tüllinghoff, Jörg Toepel, Daniel Spindler, Bruno Bühler, Pia Lindberg   +6 more
wiley   +1 more source