Results 171 to 180 of about 625,340 (244)

Proteomic analysis of the regulatory network of salt stress in Chrysanthemum. [PDF]

BMC Plant Biol
Zhang D, Wang D, Xu N, Feng S, Qian Y, Wang S, Bai Y, Zhou Y.   +7 more
europepmc   +1 more source

Copper‐Based Nanotubes That Enhance Starvation Therapy Through Cuproptosis for Synergistic Cancer Treatment

Advanced Science, EarlyView.
We designed a copper‐based nanotube (NT) with copper ionophores to induce enhanced cuproptosis. In combination with starvation therapy, the NT significantly inhibited energy metabolism in HCC cells. Our results show that the depletion of GSH by Cu2+ intensified oxidative stress and cuproptosis, resulting in ROS generation and DLAT aggregation ...
Xuan Han, Xin Zhang, Zhiping Liu, Hang Liu, Derek Wu, Yinli He, Kexin Yuan, Yi Lyu, Xiaofei Liu   +8 more
wiley   +1 more source

Enzyme-immobilized graphene oxide-based electrochemical biosensor for glutathione detection. [PDF]

RSC Adv
Ukirade N, Choudhari U, Bhapkar S, Jadhav U, Jagtap S, Rane S.   +5 more
europepmc   +1 more source

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

Advanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan, Keying Xu, Yue Gao, Sheng Huang, Xueqian Xia, Xiang Liu, Shuangxue Pan, Chunpeng Jiao, Weijian Cheng, Yong Guo, Jingwen Zhao, Jia‐Wei Shen   +11 more
wiley   +1 more source

Ranolazine as a therapeutic agent for diabetic cardiomyopathy: reducing endoplasmic reticulum stress and inflammation in type 2 diabetic rat model. [PDF]

BMC Pharmacol Toxicol
Mohyadini M, Fahimi A, Bathaie SZ, Yaghooti H.   +3 more
europepmc   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

The Manifestation of the Dual ROS-Processing and Redox Signaling Roles of Glutathione Peroxidase-like Enzymes in Development of <i>Arabidopsis</i> Seedlings. [PDF]

Antioxidants (Basel)
Bela K, Tompa B, Riyazuddin R, Horváth E, Jász K, Hajnal Á, Bangash SAK, Gallé Á, Csiszár J.   +8 more
europepmc   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

Advanced Science, EarlyView.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou, Jieqiang He, Chana Bao, Fang Zhi, Xiaoxia Shen, Yu Liu, Chaoshuo Li, Tianle Fan, Xinyue Yang, Baohua Chu, Gege Qin, Zeyuan Liu, Chuang Mei, Bin Tan, Jiancan Feng, Fengwang Ma, Mickael Malnoy, Xuewei Li, Qingmei Guan   +18 more
wiley   +1 more source

Disrupted Redox Regulation and Inflammatory Response in Pyoderma Gangrenosum. [PDF]

Life (Basel)
Georgescu SR, Matei C, Ene CD, Capusa C, Tampa M, Mitran MI, Mitran CI, Nicolae G, Nicolae I.   +8 more
europepmc   +1 more source

Single‐Cell Transcriptome Reveals Aquaporin‐Mediated Carbon Nanosol‐Induced Growth Promotion of Plants

Advanced Science, EarlyView.
Carbon nanosol (CNS) exhibits rapid root penetration capacity, enhancing plant growth through boosting stomatal density and antioxidative enzyme activity. Single‐cell transcriptomic profiling uncovers cell type‐specific gene expression patterns and developmental trajectories during CNS‐mediated growth promotion.
Lingtong Cheng, Zechao Qu, Qiansi Chen, Lin Wang, Huan Su, Jiemeng Tao, Peng Lu, Taibo Liang, Jianfeng Zhang, Peijian Cao, Jingjing Jin   +10 more
wiley   +1 more source