Results 171 to 180 of about 77,313 (353)

Regulation of System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e-\u3c/sup\u3e by Pharmacological Manipulation of Cellular Thiols [PDF]

, 2015
The cystine/glutamate exchanger (system xc-) mediates the transport of cystine into the cell in exchange for glutamate. By releasing glutamate, system xc- can potentially cause excitotoxicity.
Albano, Rebecca, Baker, David, Hjelmhaug, Julie, Lobner, Doug, Raddatz, Nicholas J.   +4 more
core   +1 more source

Can bio-inspired information processing steps be realized as synthetic biochemical processes?

, 2014
We consider possible designs and experimental realiza-tions in synthesized rather than naturally occurring bio-chemical systems of a selection of basic bio-inspired information processing steps.
Katz, Evgeny, Privman, Vladimir
core   +1 more source

Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells

Cancer Communications, EarlyView.
Ashley V. Makela, Anthony Tundo, Huiping Liu, Doug Schneider, Terry Hermiston, Pavlo Khodakivskyi, Elena Goun, Christopher H. Contag   +7 more
wiley   +1 more source

Development of Water‐Soluble 3‐Nitro‐2‐Pyridinesulfenate for Disulfide Bond Formation of Peptide Under Aqueous Conditions

Chemistry – A European Journal, EarlyView.
Highly water‐soluble Npy‐sulfenate functions as an efficient oxidizing agent for the formation of disulfide bonds in thiol‐containing peptides. The Npy‐sulfenate can be used to form a disulfide bond with a thiol‐containing peptide produced by thiol‐additive‐free NCL, thereby facilitating the one‐pot synthesis of adrenomedullin.
Akihiro Taguchi, Megumi Sakata, Ryusei Yamamoto, Hayate Shida, Saeka Kuraishi, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi   +8 more
wiley   +1 more source

Redox-manipulating nanocarriers for anticancer drug delivery: a systematic review

Journal of Nanobiotechnology
Spatiotemporally controlled cargo release is a key advantage of nanocarriers in anti-tumor therapy. Various external or internal stimuli-responsive nanomedicines have been reported for their ability to increase drug levels at the diseased site and ...
Xuan Meng, Yongli Shen, Huanyu Zhao, Xinlei Lu, Zheng Wang, Yanjun Zhao   +5 more
doaj   +1 more source

The Utility of N,N-Biotinyl Glutathione Disulfide in the Study of Protein S-Glutathiolation [PDF]

, 2005
Jonathan P. Brennan, J Miller, William Fuller, Robin Wait, Shajna Begum, Michael J. Dünn, Philip Eaton   +6 more
openalex   +1 more source

Strategy‐Level Prodrug Synthesis

Chemistry – A European Journal, EarlyView.
Prodrug approaches can be expanded by increasing options for controlling site‐selective functionalization, boosting the range of linking groups, and enhancing the chemoselectivity of reactive group incorporation. This Concept describes strategy‐level prodrug synthesis, whereby these issues are addressed at an early stage of a sequence.
Paul J. Geaneotes, Paul E. Floreancig
wiley   +1 more source

Studies on the Oxidation-reduction Potentials of 2-Mercaptopropionylglycine and Penicillamine using Thiol-Disulfide Exchange Reactions with Cysteine and Glutathione

, 1974
Shigeo Okumura, NOBUO TOSHIOKA, SHIGEO ASAKURA, MASAYUKI OHYA, SHIN-ICHI NAGAMORI   +4 more
openalex   +2 more sources

Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4′-dipyridyl disulfide [PDF]

, 2007
H. Reynaldo LÃ pez-Mirabal, Michael Thorsen, Morten C. Kielland‐Brandt, Michel B. Tolédano, Jakob R. Winther   +4 more
openalex   +1 more source

The evolution of glutathione metabolism in phototrophic microorganisms [PDF]

The low molecular weight thiol composition of a variety of phototropic microorganisms is examined in order to ascertain how evolution of glutathione (GSH) production is related to the evolution of oxygenic photosynthesis.
Buschbacher, Ralph M., Fahey, Robert C., Newton, Gerald L.   +2 more
core   +1 more source