Results 111 to 120 of about 87,212 (241)

Sex Differences in Body Composition and MASLD in Children With Overweight and Obesity

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To explore the relationships between body composition, indices of hepatic fibrosis, and sonographic evidence of hepatic steatosis in children with overweight and obesity. Methods One hundred and seventy individuals (age 12.7 ± 3.4 years, 38.2% boys) with overweight/obesity (BMI z‐score 2.02 ± 0.54) underwent bioelectrical impedance ...
Adi Uretzky   +11 more
wiley   +1 more source

Effects of a 12‐Week Mediterranean‐Type Time‐Restricted Feeding Protocol in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Randomised Controlled Trial—The ‘CHRONO‐NAFLD Project’

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 8, Page 1290-1309, April 2025.
This study corroborates the efficacy of the Mediterranean diet (MD) in ameliorating cardiometabolic risk factors such as body weight and blood pressure in patients with MASLD and overweight/obesity. The combination of a hypocaloric MD with an early 14:10 time‐restricted feeding protocol improved glycaemic control, while late eating within the MD ...
Sofia Tsitsou   +7 more
wiley   +1 more source

A study of oral metformin for the intravesical treatment of non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objectives To evaluate the effect of metformin on non‐muscle‐invasive bladder cancer (NMIBC) marker lesions. Patients and methods A phase II, open‐label, multicentre, marker lesion trial using oral metformin in patients with primary or recurrent, multiple, low‐grade Ta‐T1 NMIBC was conducted. After transurethral resection for histological confirmation,
Jons W. van Hattum   +12 more
wiley   +1 more source

Altered desensitization and internalization patterns of rodent versus human glucose‐dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The gut hormone glucose‐dependent insulinotropic polypeptide (GIP) signals via the GIP receptor (GIPR), resulting in postprandial potentiation of glucose‐stimulated insulin secretion. The translation of results from rodent studies to human studies has been challenged by the unexpected effects of GIPR‐targeting compounds.
Lærke Smidt Gasbjerg   +18 more
wiley   +1 more source

Clinical Significance of Skeletal Fat‐to‐Muscle Ratio in Idiopathic Hyperaldosteronism

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective The objective of this study is to evaluate the correlation between the fat‐to‐muscle ratio (FMR) and insulin resistance (IR) with aldosterone production among patients with idiopathic hyperaldosteronism (IHA). Methods Patients with primary aldosteronism were screened from those with secondary hypertension and then subtyped via ...
Yuhe Jiang   +6 more
wiley   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak   +4 more
wiley   +1 more source

A case of undetectable glycated hemoglobin (HbA1C) [PDF]

open access: yesQJM: An International Journal of Medicine, 2018
S N Hegde   +3 more
openaire   +3 more sources

Effect of interdisciplinary obesity care on metabolic markers and body weight in people with type 2 diabetes in a rural setting: A randomised controlled trial

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy