Results 141 to 150 of about 361,630 (339)

Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects

The Journal of Clinical Pharmacology, EarlyView.
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick, Colin Berry, Meredith A. Carpenter, Geeta Gulati, Siri Lagethon Heck, Michael A. Hinterberg, Rury R. Holman, Matthew M.Y. Lee, Torbjørn Omland, Clare Paterson, Mark C. Petrie, Naveed Sattar, Svati H. Shah, Sama Shrestha, Harald Sourij, Emma V Troth, Victoria Vinje, Stephen A. Williams   +17 more
wiley   +1 more source

Correlation between glycated hemoglobin and HOMA indices in type 2 diabetes mellitus: Prediction of Beta-cell function from glycated hemoglobin [PDF]

Journal of Medical Biochemistry, 2015
Background: The present study aimed to determine the most efficient insulin resistance function related to glycemic control expressed as glycated hemoglobin (HbA1c) in type 2 diabetes mellitus patients (T2DM). The other aim is to derive equations for the
Kadhem Al-Hakeim Hussein, Saied Abdulzahra Mohammed   +1 more
doaj  

Assessment of Glycated Hemoglobin Using A1CNow™ Point-of-Care Device as Compared to Central Laboratory Testing [PDF]

, 2008
Justin R. Arrendale, Sonia E. Cherian, Issam Zineh, Mark J. Chirico, James R. Taylor   +4 more
openalex   +1 more source

Prognostic Impact of Unplanned Total Pancreatectomy in Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background This study evaluated the clinical significance of an unplanned total pancreatectomy (TP) by comparing surgical outcomes of planned and unplanned TP for pancreatic ductal adenocarcinoma (PDAC). Methods Forty‐two patients who underwent TP for PDAC between 2009 and 2020 at the Kindai University Hospital were retrospectively analyzed ...
Dongha Lee, Keiko Kamei, Chihoko Nobori, Yuta Yoshida, Takaaki Murase, Atsushi Takebe, Takuya Nakai, Mamoru Takenaka, Takaaki Chikugo, Ippei Matsumoto   +9 more
wiley   +1 more source

A Risk Analysis for Ischemic Necrosis of the Remnant Stomach After Distal Pancreatectomy in Patients With Previous Distal Gastrectomy: A Multicenter Retrospective Survey by the Japanese Society of Pancreatic Surgery

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose The remnant stomach after distal gastrectomy (DG) which receives its blood supply mainly from the splenic artery (SPA), is at high risk for gastric ischemia following distal pancreatectomy (DP). We investigated the risk factors for ischemic necrosis of the remnant stomach (INS) during or after DP in DG patients.
Takashi Kishi, Yoshitsugu Tajima, Hikota Hayashi, Yasunari Kawabata, Kenichiro Uemura, Minako Nagai, Kohei Nishio, Kengo Fukuzawa, Shintaro Yagi, Masaaki Hidaka   +9 more
wiley   +1 more source

Salivary advanced glycated end products, their receptors, and aMMP‐8 in periodontitis patients with varying glycemic levels: A cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Advanced glycation end products (AGE) and their receptors (RAGE) have been implicated in developing periodontal complications in diabetic patients. This study aimed to identify salivary AGE, RAGE, soluble RAGE (sRAGE), and active‐matrix metalloproteinase‐8 (aMMP‐8) levels at varying glycemic levels in periodontitis patients ...
Julie Toby Thomas, Betsy Joseph, Sajit Varghese, Baiju Kamalasanan Vijayakumari, Timo Sorsa, Matti Mauramo, Sukumaran Anil, Tuomas Waltimo   +7 more
wiley   +1 more source

Glycated Hemoglobin, Diabetes, and Cardiovascular Risk in Nondiabetic Adults [PDF]

, 2010
Giuseppe Lippi, Camilla Mattiuzzi, Giovanni Targher   +2 more
openalex   +1 more source

Influence of rheumatoid arthritis on peri‐implant diseases: A longitudinal retrospective clinical and radiographic evaluation

Journal of Periodontology, EarlyView.
Abstract Background To investigate the effect of rheumatoid arthritis (RA) on the incidence of peri‐implantitis (PI) and peri‐implant mucositis (PIM). Methods Radiographic and clinical chart reviews were conducted to measure the probing depth (PD), bleeding on probing, and marginal bone loss (MBL) around the implants to diagnose peri‐implant diseases ...
Hamzeh Almashni, Era Kakar, Paolo Nava, Hom‐Lay Wang, Muhammad H. A. Saleh   +4 more
wiley   +1 more source

Working together to ensure research conducted with Aboriginal and/or Torres Strait Islander Peoples is culturally appropriate illustrated using a pharmacy‐intervention study

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Historically, health research conducted in Australia with Aboriginal and/or Torres Strait Islander Peoples has not been requested by communities. Health policies cite evidence for inclusive care including cultural perspectives.
Susan Welch, Gemma Purcell‐Khodr, Pauline Deweerd, Rebekah Moles, Alexander Viardot, Scott Daly, Kylie Lee   +6 more
wiley   +1 more source

Glycated Hemoglobin A1c, Fasting Plasma Glucose, and Two-Hour Postchallenge Plasma Glucose Levels in Relation to Carotid Intima-Media Thickness in Chinese with Normal Glucose Tolerance [PDF]

, 2011
Yun Huang, Yufang Bi, Weiqing Wang, Min Xu, Yu Xu, Mian Li, Tiange Wang, Yuhong Chen, M Kellis, Guang Ning   +9 more
openalex   +1 more source