Results 61 to 70 of about 32,524 (285)

Role of glucose variability on linear growth in children with type 1 diabetes

Endocrine Connections, 2023
Objective: Linear growth is impaired in children with type 1 diabetes (T1D) and poor metabolic control. A good metabolic control is a key therapeutic goal to prevent vascular complications and also to ensure appropriate anthropometric development during ...
Annalisa Blasetti, Valeria Castorani, Nella Polidori, Ilaria Mascioli, Francesco Chiarelli, Cosimo Giannini   +5 more
doaj   +1 more source

Understanding Glycemic Variability

Journal of Diabetology, 2021
Purpose of Review: Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease globally. Hyperglycemia, hypertension, and family history are the traditional risk factors for the initiation and progression of DKD.
AmbikaGopalakrishnan Unnikrishnan, Charan Bale, Arjun Lal Kakrani, VedavatiBharat Purandare   +3 more
openaire   +3 more sources

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

Physiological pH Transition‐Driven Protein Corona Dynamics Regulate Cellular Uptake and Inflammatory Responses of Silica Nanoparticles

Advanced Science, EarlyView.
Physiological pH transitions modulate protein corona dynamics on nanoparticles, altering their cellular uptake and inflammatory responses. Acidic pHs enhance protein adsorption, induce structural changes, and promote cellular uptake. Simultaneously, inflammatory responses are reduced due to altered protein composition, including decreased ...
Yuting Ge, Fangqin Fu, Yu Gao, Tianchang He, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +7 more
wiley   +1 more source

Correlation Between Glycemic Variability and Diabetic Complications: A Narrative Review

International Journal of General Medicine, 2023
Lining Huang,1 Ying Pan,1 Kaixin Zhou,2 Hongying Liu,3 Shao Zhong1 1Department of Endocrinology, Gusu School, Nanjing Medical University, The First People’s Hospital of Kunshan, Kunshan, 215300, People’s Republic of China; 2Guangzhou Laboratory ...
Huang L, Pan Y, Zhou K, Liu H, Zhong S
doaj  

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Continuous glucose monitoring: indications, data interpretation and making therapeutic decisions

Revista de la Sociedad Argentina de Diabetes, 2020
The tools to assess the degree of glycemic control were modified lately. Glycosylated Hemoglobin (HbA1c), the gold standard, reflects the glycemic control of the last 3 months retrospectively, without expressing glycemic variability.
León Litwak, Nancy Carreño, Rodrigo Carnero, Alejandro Dain, Luis Grosembacher, Carla Musso, Adrián Proietti, Lucas Rista, Gabriela Rovira, Graciela Rubin, María Ruiz, Antonio Saleme, Liliana Trifone, José Costa Gil   +13 more
doaj   +1 more source

Effects of Melatonin on Glycemic Variability in Type 2 Diabetes Mellitus: Protocol for a Crossover, Double-Blind, Placebo-Controlled Trial

JMIR Research Protocols, 2023
BackgroundGlycemic variability is recognized as a significant factor contributing to the development of micro- and macrovascular complications in individuals with type 2 diabetes mellitus (T2DM).
Wagner Martorina, Almir Tavares
doaj   +1 more source

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li, Eduardo H. Gilglioni, Wadsen St‐Pierre‐Wijckmans, Leila Hosseinzadeh, Christelle Veyrat‐Durebex, Sumeet Pal Singh, Roberto Coppari, Latifa Bakiri, Esteban N. Gurzov   +8 more
wiley   +1 more source

Nerve conduction study of the association between glycemic variability and diabetes neuropathy

Diabetology & Metabolic Syndrome, 2018
Background It remains unclear whether glycemic variability is related to diabetes microvascular disease, especially diabetes peripheral neuropathy (DPN).
Miho Akaza, Itaru Akaza, Tadashi Kanouchi, Tetsuo Sasano, Yuki Sumi, Takanori Yokota   +5 more
doaj   +1 more source