Results 151 to 160 of about 10,324 (247)

Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency

open access: yesEpilepsia, EarlyView.
Abstract Objective Some ion channel genes linked to developmental and epileptic encephalopathy (DEE) are also linked to cardiac arrhythmia, leading to the hypothesis that predisposition to cardiac arrhythmias may contribute to the complex disease presentation of DEE and possibly to the mechanism of sudden unexpected death in epilepsy.
Roberto Ramos‐Mondragon   +9 more
wiley   +1 more source

CaMKIIβ insufficiency disrupts cortical networks, producing aberrant low‐gamma oscillations and seizure susceptibility

open access: yesEpilepsia, EarlyView.
Abstract Objective Pathogenic variants in the calcium/calmodulin‐dependent protein kinase II B gene (CAMK2B) have been associated with neurodevelopmental disorders, including epilepsy, yet the mechanisms underlying cortical dysfunction remain largely unclear.
Hiroki Mutoh   +3 more
wiley   +1 more source

Protective effects of adiponectin receptor agonists against equine lamellar endoplasmic reticulum stress

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Lamellar endoplasmic reticulum (ER) stress occurs in hyperinsulinemia‐associated and sepsis‐related laminitis. Adiponectin is associated with reduced laminitis risk and inhibits ER stress in other species. Objectives To induce ER stress in ex vivo equine lamellar cells using pharmacological agents.
Marine A. Barnabé   +6 more
wiley   +1 more source

Comparative studies on D-Glyceraldehyde-3-phosphate dehydrogenases : VIII. A Study of the Essential Zn Ions of the Enzyme

open access: yes, 1959
The inhibitory action of 1,10-phenanthrolene on the D-glyceraldehyde-3-pbosphate and D-glyceraldehyde oxidation by D-glyceraldehyde-3-phosphate dehydrogenases isolated in crystalline form from rabbit, bovine and pig muscle, from baker’s and brewer’s ...
Keleti, Tamás, Telegdi, Marianna
core  

Light‐Driven Butyrate Production by a Probiotic Clostridium tyrobutyricum Enabled by a Cell‐Semiconductor Hybrid Interface

open access: yesFood Chemistry International, EarlyView.
This schematic illustrates a light‐driven biohybrid system where CdS nanoparticles, mineralized on the probiotic Clostridium tyrobutyricum, inject photoelectrons to elevate intracellular NADH. This boosts the flux through key NADH‐dependent enzymes (GapA, Hbd, and Bcd), reprogramming metabolism to enhance butyrate yield by 33.2% and selectivity to 95.7%
Qianru Zhao   +3 more
wiley   +1 more source

Carbohydrate metabolism of Xylella fastidiosa: Detection of glycolytic and pentose phosphate pathway enzymes and cloning and expression of the enolase gene

open access: yesGenetics and Molecular Biology, 2003
The objective of this work was to assess the functionality of the glycolytic pathways in the bacterium Xylella fastidiosa. To this effect, the enzymes phosphoglucose isomerase, aldolase, glyceraldehyde-3-phosphate dehydrogenase and pyruvate kinase of the
Facincani Agda Paula   +6 more
doaj  

Interaction of Glyceraldehyde-3-Phosphate Dehydrogenase With Isolated Microsomal Subfractions of Skeletal Muscle

open access: yes, 1985
A protein of subunit Mr 34,000 (corrected here and subsequently to 36,000) has been isolated from a muscle homogenate which catalyzes the formation of the triad junction from isolated transverse tubules and terminal cisternae.
Caswell, Anthony H., Corbett, Adrian M.
core  

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

open access: yesIbrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou   +6 more
wiley   +1 more source

Lung Cancer Patients Display Increased Expression of Bovine Meat and Milk Factor (BMMF) Proteins in Peritumor Alveolar Macrophages

open access: yesInternational Journal of Cancer, EarlyView.
Plasmid‐like DNA sequences frequently found in bovine milk and serum have been proposed as infectious agents promoting indirect carcinogenesis. This multi‐omics study detected immune cells positive for these bovine meat and milk factors (BMMFs) in patients with lung cancer, with BMMF expression inversely correlated with smoking intensity.
Nives Cecere   +17 more
wiley   +1 more source

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