Absorption and metabolism of fructose and its relationship with human health
Fructose is a monosaccharide, which is greatly sweeter than glucose and sucrose. In recent years, high fructose corn syrup has been widely used in beverages and food industry globally.
CAI Wenwen, LI Duo
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Iodination of glyceraldehyde 3-phosphate dehydrogenase [PDF]
1. A high degree of homology in the positions of tyrosine residues in glyceraldehyde 3-phosphate dehydrogenase from lobster and pig muscle, and from yeast, prompted an examination of the reactivity of tyrosine residues in the enzyme. 2. Iodination of the enzyme from lobster muscle with low concentrations of potassium tri-[125I]-iodide led to the ...
J O, Thomas, J I, Harris
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Electrooxidation of Anhydrous Glycerol: Kinetics and Selectivity
As a by‐product of biofuel production, glycerol needs to find its use in various applications, for example, as a substrate for electrosynthesis of more valuable chemicals. The glycerol oxidation reaction (GOR) in aqueous media is technologically feasible
Laela Ezra +4 more
doaj +1 more source
Urine glyceraldehyde excretion is elevated in the renal Fanconi syndrome
Urine glyceraldehyde excretion is elevated in the renal Fanconi syndrome. We analyzed urinary constituents using GC/MS in 16 children with the renal Fanconi syndrome and 13 normal individuals.
Conley, Susan B. +5 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Background Host proteins are incorporated inside human immunodeficiency virus type 1 (HIV-1) virions during assembly and can either positively or negatively regulate HIV-1 infection.
Kishimoto Naoki +5 more
doaj +1 more source
Refolding of a thermostable glyceraldehyde dehydrogenase for application in synthetic cascade biomanufacturing. [PDF]
The production of chemicals from renewable resources is gaining importance in the light of limited fossil resources. One promising alternative to widespread fermentation based methods used here is Synthetic Cascade Biomanufacturing, the application of ...
Fabian Steffler, Volker Sieber
doaj +1 more source
The presence of NADPH-glyceraldehyde 3-phosphate oxidoreductase in macrophages
The existence of an NADPH-oxidoreductase which utilizes D-glyceraldehyde 3-phosphate as substrate has been demonstrated in mouse peritoneal macrophages. D-Glyceraldehyde could also serve as substrate, albeit with a 10-fold lower efficiency.
Gershon, David +5 more
core +1 more source

