Results 41 to 50 of about 557,910 (260)
Fibers Obtained from Alginate, Chitosan and Hybrid Used in the Development of Scaffolds [PDF]
Materials Research, 2017 The main aim of this study was to develop scaffolds based on alginate, chitosan and hybrid fibers with and without glycerol. The scaffolds developed underwent assessments for tensile property, swelling ratio and weight loss, cellular viability ...
Daniela Camargo Furuya +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Crude glycerol esterification using biomass-derived carbon acid catalysts
Next MaterialsIn this work, carbons obtained from peanut shells (PC), activated with KOH (APC) and functionalized with H2SO4 (PC-F and APC-F, respectively) were evaluated as catalysts in the esterification of crude glycerol with acetic acid to obtain monoacetyl ...
Federico M. Perez +5 more
doaj +1 more source
Glycerol affects root development through regulation of multiple pathways in Arabidopsis. [PDF]
PLoS ONE, 2014 Glycerol metabolism has been well studied biochemically. However, the means by which glycerol functions in plant development is not well understood. This study aimed to investigate the mechanism underlying the effects of glycerol on root development in ...
Jun Hu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Biotechnology for Biofuels, 2019 Background Due to its inevitable formation during biodiesel production and its relatively high degree of reduction, glycerol is an attractive carbon source for microbial fermentation processes.
Maximilian R. Aßkamp +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Synthesis of α-Glycerol Mono Caprylate from Protected Glycerol [PDF]
E3S Web of ConferencesThe synthesis of α-glycerol mono caprylate from protected glycerol has been carried out through a two-step reaction process. The transesterification reaction of methyl caprylate and protected glycerol (ratio 1:4) in the presence of 5% K2CO3 (w/w of the ...
Nitbani Febri Odel +5 more
doaj +1 more source